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zeleny's bookmarks matching tag aging

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DNA repair is limiting for haematopoietic stem cells during ageing.

Anastasia Nijnik et al.

Nature 447 (7145), 686-90 (07 Jun 2007)

info:pmid/17554302 | info:doi/10.1038/nature05875

Posted by zeleny and 3 others to DNA repair aging on Sun Jun 10 2007 at 15:20 UTC | info | related

OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.

Irina Kovtun et al.

Nature 447 (7143), 447-52 (24 May 2007)

info:pmid/17450122 | info:doi/10.1038/nature05778

Posted by zeleny and 4 others with 1 comment to DNA repair aging on Sun Jun 10 2007 at 14:41 UTC | info | related

A DNA damage checkpoint response in telomere-initiated senescence.

Fabrizio d'Adda di Fagagna et al.

Nature. 426 (6963), 194-8 (13 Nov 2003)

info:pmid/14608368 | info:doi/10.1038/nature02118

Posted by zeleny to senescence aging haveX on Wed Mar 08 2006 at 17:10 UTC | info | related

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

G P Dimri et al.

Proceedings of the National Academy of Sciences of the United States of America. 92 (20), 9363-7 (26 Sep 1995)

info:pmid/7568133

Posted by zeleny to β-galactosidase senescence assay aging on Wed Mar 08 2006 at 15:20 UTC | info | related

The limitations and validities of senescence associated-beta-galactosidase activity as an aging marker for human foreskin fibroblast Hs68 cells.

Nae-Cherng Yang and Miao-Lin Hu

Experimental gerontology. 40 (10), 813-9 (Oct 2005)

info:pmid/16154306 | info:doi/10.1016/j.exger.2005.07.011

Posted by zeleny to senescence assay cellular senescence aging beta-galactosidases on Sat Mar 04 2006 at 20:11 UTC | info | related

SA beta Gal staining: biomarker or delusion.

V J Cristofalo

Experimental gerontology. 40 (10), 836-8 (Oct 2005)

info:pmid/16181758 | info:doi/10.1016/j.exger.2005.08.005

Posted by zeleny to senescence assay cellular senescence aging beta-galactosidases on Sat Mar 04 2006 at 20:05 UTC | info | related

The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel.

Q Chang et al.

Science 310 (5747), 490-3 (21 Oct 2005)

info:pmid/16239475 | info:doi/10.1126/science.1114245

Posted by zeleny to aging glycoside hydrolase on Mon Nov 14 2005 at 09:13 UTC | info | related

Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides.

Osamu Tohyama et al.

J Biol Chem 279 (11), 9777-84 (12 Mar 2004)

info:pmid/14701853 | info:doi/10.1074/jbc.M312392200

Posted by zeleny with 1 comment to glycoside hydrolase aging on Mon Nov 14 2005 at 08:02 UTC | info | related

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