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Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: structure of lck/imatinib complex.
Marc D Jacobs, Paul R Caron, and Brian J Hare
Proteins 70 (4), 1451-60 (Mar 2008)
 
Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors.
Kieron Brown et al.
The Journal of biological chemistry 279 (18), 18727-32 (30 Apr 2004)
 
Selective targeting of ITK blocks multiple steps of HIV replication.
Julie A Readinger et al.
Proceedings of the National Academy of Sciences of the United States of America, (28 Apr 2008)
Posted by telconia with 1 comment to kinases HIV on Wed Apr 30 2008 at 19:24 UTC | info | related
 
A kinase-focused compound collection: compilation and screening strategy.
Dongyu Sun et al.
Chemical biology & drug design 67 (6), 385-94 (Jun 2006)
Posted by telconia and 2 others to kinases Library design on Thu Mar 06 2008 at 17:54 UTC | info | related
 
Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors.
Yunsong Tong et al.
Bioorganic & medicinal chemistry 15 (7), 2759-67 (01 Apr 2007)
 
Crystallography for protein kinase drug design: PKA and SRC case studies.
Christine B Breitenlechner, Dirk Bossemeyer, and Richard A Engh
Biochimica et biophysica acta. 1754 (1-2), 38-49 (30 Dec 2005)
 
Identification of inhibitors of protein kinase B using fragment-based lead discovery.
Gordon Saxty et al.
Journal of medicinal chemistry 50 (10), 2293-6 (17 May 2007)
Posted by telconia to Fragment kinases on Mon Jan 14 2008 at 21:07 UTC | info | related
 
A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera.
Thomas G Davies et al.
Journal of molecular biology 367 (3), 882-94 (30 Mar 2007)
Posted by telconia to kinases on Mon Jan 14 2008 at 20:56 UTC | info | related
 
Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases.
Ruth Brenk et al.
ChemMedChem, (06 Dec 2007)

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