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Primordial spliceosomal introns were probably U2-type.

Malay Kumar Basu, Igor B Rogozin, and Eugene V Koonin

Trends in genetics : TIG 24 (11), 525-8 (Nov 2008)

info:pmid/18824272 | info:doi/10.1016/j.tig.2008.09.002

Posted by smount to 4WM09 U12 spliceosome evolution on Sun Jun 14 2009 at 02:15 UTC | info | related

PLoS Computational Biology: Sm/Lsm Genes Provide a Glimpse into the Early Evolution of the Spliceosome

www.ploscompbiol.org

Posted by smount to 4WM09 Sm_proteins spliceosome evolution on Sun Jun 14 2009 at 02:13 UTC | info | related

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia.

Stephen Huffaker et al.

Nature medicine 15 (5), 509-18 (May 2009)

info:pmid/19412172 | info:doi/10.1038/nm.1962

Posted by smount to Polymorphisms splicing brain on Wed May 27 2009 at 05:37 UTC | info | related

Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.

Andrew D Johnson et al.

Pharmacogenetics and genomics 18 (9), 781-91 (Sep 2008)

info:pmid/18698231 | info:doi/10.1097/FPC.0b013e3283050107

Posted by smount to pop_gen Polymorphisms snp splicing on Wed May 27 2009 at 05:34 UTC | info | related

Stem cell transcriptome profiling via massive-scale mRNA sequencing

Nicole Cloonan et al.

Nature Methods, published online 30 May 2008

info:pmid/18516046 | info:doi/10.1038/nmeth.1223

Posted by smount and 11 others to 4MLTL mRNA-Seq solid mouse genotyping genomics on Wed May 27 2009 at 05:30 UTC | info | related

The functional consequences of alternative promoter use in mammalian genomes.

Ramana V Davuluri et al.

Trends in genetics : TIG 24 (4), 167-77 (Apr 2008)

info:pmid/18329129 | info:doi/10.1016/j.tig.2008.01.008

Posted by smount to alternative_promoter_use 4MLTL transcription genomics on Tue May 26 2009 at 13:44 UTC | info | related

The efficiency of nonsense-mediated mRNA decay is an inherent character and varies among different cells.

Liat Linde et al.

European journal of human genetics : EJHG 15 (11), 1156-62 (Nov 2007)

info:pmid/17625509 | info:doi/10.1038/sj.ejhg.5201889

Posted by smount to 4MLTL genetic_association NMD variation on Tue May 26 2009 at 02:09 UTC | info | related

Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns.

Henning Tidow et al.

Structure (London, England : 1993) 17 (2), 294-302 (13 Feb 2009)

info:pmid/19217400 | info:doi/10.1016/j.str.2008.11.013

Posted by smount to U12 structure Protein on Thu Mar 26 2009 at 02:16 UTC | info | related

SCNM1, a putative RNA splicing factor that modifies disease severity in mice.

David A Buchner, Michelle Trudeau, and Miriam H Meisler

Science (New York, N.Y.) 301 (5635), 967-9 (15 Aug 2003)

info:pmid/12920299 | info:doi/10.1126/science.1086187

Posted by smount to 4-688I synthetic_phenotypes mouse splicing genetics 4MLTL on Tue Mar 24 2009 at 01:37 UTC | info | related

Evidence for a direct role of the disease modifier SCNM1 in splicing.

Viive M Howell et al.

Human molecular genetics 16 (20), 2506-16 (15 Oct 2007)

info:pmid/17656373 | info:doi/10.1093/hmg/ddm206

Posted by smount to mouse splicing genetics 4MLTL on Tue Mar 24 2009 at 01:35 UTC | info | related

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