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Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1.

Jidong Zhu, John Blenis, and Junying Yuan

Proceedings of the National Academy of Sciences of the United States of America, (01 May 2008)

info:pmid/18451027 | info:doi/10.1073/pnas.0802785105

Posted by sennoma to Mad1 Myc MAPK Akt PI3K on Sun May 04 2008 at 02:11 UTC | info | related

DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.

Jing An et al.

Molecular cancer 7 (1), 32 (22 Apr 2008)

info:pmid/18426604 | info:doi/10.1186/1476-4598-7-32

Posted by sennoma to Myc stabilization c-Myc DNA-PK on Wed Apr 23 2008 at 21:23 UTC | info | related

Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.

Miriam Marqués et al.

Molecular and cellular biology 28 (8), 2803-14 (Apr 2008)

info:pmid/18285463 | info:doi/10.1128/MCB.01786-07

Posted by sennoma to s g1 G0 cell cycle entry cell cycle PI3K on Tue Apr 22 2008 at 21:25 UTC | info | related

c-Myc inhibits Ras-mediated differentiation of pheochromocytoma cells by blocking c-Jun up-regulation.

José P Vaqué et al.

Molecular cancer research : MCR 6 (2), 325-39 (Feb 2008)

info:pmid/18314492 | info:doi/10.1158/1541-7786.MCR-07-0180

Posted by sennoma to PC12 cells differentiation ras c-Myc jun on Mon Apr 21 2008 at 22:08 UTC | info | related

CDK5-mediated phosphorylation of c-MYC on SER62 is essential in transcriptional activation of cyclin B1 by cyclin G1.

Haeng Ran Seo et al.

The Journal of biological chemistry, (11 Apr 2008)

info:pmid/18408012 | info:doi/10.1074/jbc.M800987200

Posted by sennoma to Myc S62 Myc phosphorylation cdk5 on Tue Apr 15 2008 at 22:29 UTC | info | related

New functions for PI3K in the control of cell division.

Amit Kumar and Ana C Carrera

Cell cycle (Georgetown, Tex.) 6 (14), 1696-8 (May 2007)

info:pmid/17598985

Posted by sennoma to autoimmunity cancer g1 cell cycle PI3K on Thu Apr 10 2008 at 20:36 UTC | info | related

Genes proximal and distal to MYCN are highly expressed in human neuroblastoma as visualized by comparative expressed sequence hybridization.

Cornelia Stock et al.

The American journal of pathology 172 (1), 203-14 (Jan 2008)

info:pmid/18165268 | info:doi/10.2353/ajpath.2008.061263

Posted by sennoma to proximal and distal genes N-myc on Mon Apr 07 2008 at 02:24 UTC | info | related

Global Identification of Myc Target Genes Reveals Its Direct Role in Mitochondrial Biogenesis and Its E-Box Usage In Vivo.

Jonghwan Kim, Ji-Hoon Lee, and Vishwanath R Iyer

PLoS ONE 3 (3), e1798 (2008)

info:pmid/18335064 | info:doi/10.1371/journal.pone.0001798

Posted by sennoma to mitochondria E box myc targets Myc on Fri Mar 14 2008 at 00:48 UTC | info | related

Pam (Protein associated with Myc) functions as an E3 Ubiquitin ligase and regulates TSC/mTOR signaling.

Sangyeul Han et al.

Cellular signalling, (01 Feb 2008)

info:pmid/18308511 | info:doi/10.1016/j.cellsig.2008.01.020

Posted by sennoma to hamartin tuberin ubn ligase mTOR Myc PAM on Tue Mar 04 2008 at 00:22 UTC | info | related

MYC in mammalian epidermis: how can an oncogene stimulate differentiation?

Fiona M Watt, Michaela Frye, and Salvador Aznar Benitah

Nature reviews. Cancer 8 (3), 234-42 (Mar 2008)

info:pmid/18292777 | info:doi/10.1038/nrc2328

Posted by sennoma to review differentiation Myc on Sun Feb 24 2008 at 01:34 UTC | info | related

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