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Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells.
Aruna Jaiswal et al.
Oncogene 21 (55), 8414-27 (05 Dec 2002)
info:pmid/12466962 | info:doi/10.1038/sj.onc.1205947
La curcumine semble degrader la beta catenin via caspase 3 et arreter le cycle de cellule de cancer de colon. Mais elle ne semble pas tres specifique et inhibe la transcription en general.
Posted by rastarokko to cells. cancer colon arrest growth adhesion curcumin Catenin beta on Wed Oct 31 2007 at 16:03 UTC | info | related

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