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pedrohorna's bookmarks matching tag "JAK Stat"
 
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Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-{beta}1
Ichiko Kinjyo et al.
The Journal of Experimental Medicine 203 (4), 1021-31 (17 Apr 2006)
T-cells lacking Socs3 are shifted towards the differentiation of IL-10/TGF-b producing Th3 T-cells, underscoring the importance of Stat3 on the generation of regulatory T-cells.
Posted by pedrohorna to CD4 T-cells JAK Stat T-cell signaling on Tue May 02 2006 at 19:46 UTC | info | related
 
SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling
Kevin Evel-Kabler et al.
Journal of Clinical Investigation 116 (1), 90-100 (01 Jan 2006)
Immunization with Trp2 pulsed, LPS matured, SOCS1 siRNA treated DCs + 1 dose of systemic TLR ligand causes vitiligo and B16 rejection.
Posted by pedrohorna and 1 other with 1 comment to dendritic cells T-cell tolerance signaling tolerance reversal JAK Stat cancer vaccines immunotherapy on Mon Mar 06 2006 at 22:35 UTC | info | related
 
STAT-1-mediated repression of monocyte interleukin-10 gene expression in vivo
Jeffrey B. VanDeusen et al.
European Journal of Immunology 36 (3), 623-30 (2006)
info:doi/10.1002/eji.200535241
Posted by pedrohorna to monocytes IL-10 JAK Stat on Tue Feb 28 2006 at 18:57 UTC | info | related
 
STAT4: a critical regulator of inflammation in vivo.
Mark H Kaplan
Immunologic research. 31 (3), 231-42 (2005)
info:pmid/15888914
Posted by pedrohorna to review signaling JAK Stat on Tue Feb 28 2006 at 17:53 UTC | info | related
 
A critical role for Stat3 signaling in immune tolerance.
Fengdong Cheng et al.
Immunity. 19 (3), 425-36 (Sep 2003)
info:pmid/14499117
Macrophages and DCs increase their antigen presenting capabilities when stat3 signaling is disrupted. Also, mice with a disruption of Stat3 in macrophages and neutrophils are resistant to tolerance induction with high dose peptide. Neverhteless, the mechanism of this in-vivo phenomenon remains obscure.
Posted by pedrohorna to T-cell tolerance macrophages tolerance reversal CD4 T-cells JAK Stat on Sat Feb 18 2006 at 00:15 UTC | info | related
 
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.
K Takeda et al.
Immunity 10 (1), 39-49 (Jan 1999)
info:pmid/10023769
Original paper describing LysMCre/Stat3 KO mice
Posted by pedrohorna and 1 other to macrophages JAK Stat on Thu Feb 02 2006 at 20:35 UTC | info | related
 
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
Marcin Kortylewski et al.
Nat Med 11 (12), 1314-21 (Dec 2005)
info:doi/10.1038/nm1325
Posted by pedrohorna with 1 comment to dendritic cells JAK Stat on Thu Dec 22 2005 at 21:58 UTC | info | related
 
REGULATION OF GENE-ACTIVATION PATHWAYS BY PIAS PROTEINS IN THE IMMUNE SYSTEM
Ke Shuai and Bin Liu
Nature Reviews Immunology 5 (8), 593-605 (Aug 2005)
info:doi/10.1038/nri1667
Posted by pedrohorna and 1 other to JAK Stat review on Tue Dec 06 2005 at 03:39 UTC | info | related
 
IL-6-STAT3 Controls Intracellular MHC Class II alphabeta Dimer Level through Cathepsin S Activity in Dendritic Cells.
Hidemitsu Kitamura et al.
Immunity 23 (5), 491-502 (Nov 2005)
info:pmid/16286017 | info:doi/10.1016/j.immuni.2005.09.010
IL-6 decreases the level of intracellular MHC II through Stat3 activation.
Posted by pedrohorna and 1 other with 1 comment to dendritic cells JAK Stat on Sun Dec 04 2005 at 02:35 UTC | info | related
 
IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation.
Sung-Joo Park et al.
J Immunol 173 (6), 3844-54 (15 Sep 2004)
info:pmid/15356132
Posted by pedrohorna and 1 other to dendritic cells JAK Stat on Sun Dec 04 2005 at 02:23 UTC | info | related

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