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Structural biology: RNA switches function
Steve Reichow and Gabriele Varani
Nature 441 (7097), 1054-5 (29 Jun 2006)
Riboswitches in UTR of mRNA regulate metabolic protein expression by selectively binding metabolites that mask/unmask translation initiation signals
Posted by lyonsden and 1 other to RNA world riboswitch RNA on Thu Jun 29 2006 at 18:34 UTC | info | related
 
Introns and the origin of nucleus–cytosol compartmentalization
Introns and the origin of nucleusâcytosol compartmentalization
William Martin and Eugene Koonin
Nature 440 (7080), 41-5 (02 Mar 2006)
Proposes that the slow rate of intron splicing in Euks was the driving selection to form the nuclear membrane. The nuclear membrane keeps translation seprate from transcription and provides a place for splicing to occure.
 
Origins of DNA: Base invaders
John Whitfield
Nature 439 (7073), 130-1 (12 Jan 2006)
Hypothetical role for viruses in the evolution of DNA
Posted by lyonsden and 2 others with 1 comment to virus DNA RNA world on Wed Jan 11 2006 at 20:59 UTC | info | related
 
Chemical biology: Bring them back alive
Michael Yarus
Nature 438 (7064), 40 (03 Nov 2005)
ribozyme aldol chemistry -- essential for sugar metabolism
Posted by lyonsden and 1 other to ribozyme RNA world on Thu Nov 03 2005 at 18:29 UTC | info | related
 
RNA-Catalyzed RNA Polymerization: Accurate and General RNA-Templated Primer Extension
Wendy Johnston et al.
Science 292 (5520), 1319-25 (18 May 2001)
Created a synthetic ribopolymerase
Posted by lyonsden to ribopolymerase RNA world on Wed Nov 02 2005 at 07:07 UTC | info | related
 
Molecular evolutionBooting up life
Gerald Joyce
Nature 420 (6913), 278-9 (21 Nov 2002)
Summary of computer simulated experiment to show that genome size and replication speed increases over simulated evolutionary time
Posted by lyonsden and 1 other with 1 comment to Origin of Life RNA world on Wed Nov 02 2005 at 07:02 UTC | info | related
 
Real ribozymes suggest a relaxed error threshold
Adam Kun, Mauro Santos, and Eors Szathmary
Nat Genet 37 (9), 1008-11 (Sep 2005)
Discuses the error tolerance in ribozymes. This allows for "larger" ribo-genomes
Posted by lyonsden and 1 other to RNA world on Wed Nov 02 2005 at 06:41 UTC | info | related
 
Stirring the primordial soup
William Taylor
Nature 434 (7034), 705 (07 Apr 2005)
Introduces the problem of RNA replication for the RNA world.
Posted by lyonsden with 1 comment to RNA world Origin of Life on Wed Nov 02 2005 at 06:20 UTC | info | related
 
The onset of selection
Christian de Duve
Nature 433 (7026), 581-2 (Feb 2005)

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