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Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type K-ras oncogene but has different effects on protein phosphorylation and induction of apoptosis

Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wildtype Kras oncogene but has different effects on protein phosphorylation and induction of apoptosis

C Müller et al.

International journal of oncology. 12 (3), 717-23 (Mar 1998)

info:pmid/9472115

DA - 19980414 IS - 1019-6439 (Print) LA - eng PT - Journal Article RN - 0 (Antineoplastic Agents) RN - 0 (Neoplasm Proteins) RN - 75330-75-5 (Lovastatin) RN - EC 3.6.5.2 (HRAS protein, human) RN - EC 3.6.5.2 (Proto-Oncogene Proteins p21(ras)) SB - IM

Posted by jchardwick to Proto-Oncogene Proteins p21(ras) Lovastatin Pancreatic Neoplasms Point Mutation Antineoplastic Agents Amino Acid Substitution Neoplasm Proteins drug effects Cell Line Tumor Cells Cultured BIOSYNTHESIS cell division humans Research Support Non-U.S.Gov't Pharmacology flow cytometry ras Drug Phosphorylation cell cycle metabolism human Genes Apoptosis genetics proteins cells on Mon Nov 06 2006 at 15:38 UTC | info | related

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