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jchardwick's bookmarks matching tag Enzymology
 
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The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity
The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMGCoA reductase activity
Ada Staal et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 18 (1), 88-96 (Jan 2003)
info:pmid/12510809
DA - 20030103 IS - 0884-0431 (Print) LA - eng PT - Journal Article RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) RN - 0 (Pyridines) RN - 0 (cerivastatin) RN - 7440-70-2 (Calcium) RN - 75330-75-5 (Lovastatin) RN - 79902-63-9 (Simvastatin) RN - 81093-37-0 (Pravastatin) RN - EC 1.1.1.- (Hydroxymethylglutaryl CoA Reductases) SB - IM
Posted by jchardwick to thyroidectomy simvastatin Non-U.S.Gov't Research Support Sprague-Dawley rats Rabbits Pyridines Protein Isoprenylation prevention & control pravastatin Pharmacology parathyroidectomy osteogenesis osteoclasts metabolism Male Lovastatin In Vitro Hydroxymethylglutaryl-CoA Reductase Inhibitors Hydroxymethylglutaryl CoA Reductases female Enzymology drug effects Drug Calcium Bone Resorption BIOSYNTHESIS animals on Mon Nov 06 2006 at 15:38 UTC | info | related
 
Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice
Prevention of 12dimethylhydrazineinduced colon tumorigenesis by HMGCoA reductase inhibitors pravastatin and simvastatin in ICR mice
T Narisawa et al.
Carcinogenesis. 15 (9), 2045-8 (Sep 1994)
info:pmid/7923600
DA - 19941102 IS - 0143-3334 (Print) LA - eng PT - Journal Article RN - 0 (Anticarcinogenic Agents) RN - 0 (Carcinogens) RN - 0 (Dimethylhydrazines) RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) RN - 540-73-8 (1,2-Dimethylhydrazine) RN - 57-88-5 (Cholesterol) RN - 75330-75-5 (Lovastatin) RN - 79902-63-9 (Simvastatin) RN - 81093-37-0 (Pravastatin) SB - IM
Posted by jchardwick to tumor therapeutic use simvastatin Non-U.S.Gov't Research Support prevention & control pravastatin Inbred ICR mice Lovastatin incidence Hydroxymethylglutaryl-CoA Reductase Inhibitors female Enzymology Dimethylhydrazines COMPARATIVE STUDY Colonic Neoplasms cholesterol chemically induced Carcinogens blood Anticarcinogenic Agents animals analogs & derivatives Adenocarcinoma 2-Dimethylhydrazine 1 on Mon Nov 06 2006 at 15:38 UTC | info | related

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