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jcarroll42's bookmarks matching tag inclusions
 
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Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases.
M Y Sherman and A L Goldberg
Neuron. 29 (1), 15-32 (Jan 2001)
info:pmid/11182078
Posted by jcarroll42 with 1 comment to inclusions on Tue Jan 17 2006 at 17:02 UTC | info | related
 
Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody.
David W Colby et al.
Proc Natl Acad Sci U S A 101 (51), 17616-21 (21 Dec 2004)
info:pmid/15598740 | info:doi/10.1073/pnas.0408134101
Posted by jcarroll42 to Intrabodies inclusions on Sat Dec 03 2005 at 00:03 UTC | info | related
 
Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation.
Aaron B Bowman et al.
Hum Mol Genet 14 (5), 679-91 (01 Mar 2005)
info:pmid/15661755 | info:doi/10.1093/hmg/ddi064
Posted by jcarroll42 and 1 other to Protein Degredation inclusions sca on Fri Dec 02 2005 at 23:31 UTC | info | related
 
Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity.
Michael D Kaytor, Keith D Wilkinson, and Stephen T Warren
J Neurochem 89 (4), 962-73 (May 2004)
info:pmid/15140195 | info:doi/10.1111/j.1471-4159.2004.02376.x
Posted by jcarroll42 to Protein Degredation inclusions on Fri Dec 02 2005 at 23:28 UTC | info | related
 
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
F Saudou et al.
Cell 95 (1), 55-66 (02 Oct 1998)
info:pmid/9778247
Posted by jcarroll42 to Nuclear Huntingtin inclusions on Fri Dec 02 2005 at 23:27 UTC | info | related
 
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate et al.
Nature. 431 (7010), 805-10 (14 Oct 2004)
info:pmid/15483602 | info:doi/10.1038/nature02998
Posted by jcarroll42 and 2 others to inclusions on Fri Dec 02 2005 at 23:26 UTC | info | related
 
Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells.
C L Wellington et al.
J Biol Chem 275 (26), 19831-8 (30 Jun 2000)
info:pmid/10770929 | info:doi/10.1074/jbc.M001475200
Posted by jcarroll42 to Caspases in HD inclusions caspase on Fri Dec 02 2005 at 22:48 UTC | info | related
 
Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions.
Elizabeth J Slow et al.
Proc Natl Acad Sci U S A 102 (32), 11402-7 (09 Aug 2005)
info:pmid/16076956 | info:doi/10.1073/pnas.0503634102
Posted by jcarroll42 to Shortstop YAC128 inclusions on Fri Dec 02 2005 at 22:30 UTC | info | related

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