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Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain.
M Scheinin et al.
Brain research. Molecular brain research 21 (1-2), 133-49 (Jan 1994)
info:pmid/8164514
Good article. Says that alpha2A receptors are the presynaptic ones.
Posted by chris979 to alpha2 presynaptic on Sun Jun 17 2007 at 04:35 UTC | info | related
 
The alpha(2A)-adrenergic agonist guanfacine improves visuomotor associative learning in monkeys.
Min Wang, Jin-Zhao Ji, and Bao-Ming Li
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 29 (1), 86-92 (Jan 2004)
info:pmid/12931141 | info:doi/10.1038/sj.npp.1300278
says that guanfacine is alpha2A selective.
Posted by chris979 to guanfacine alpha2 on Sun Jun 17 2007 at 03:33 UTC | info | related
 
[3H]-MK 912 binding delineates two alpha 2-adrenoceptor subtypes in rat CNS one of which is identical with the cloned pA2d alpha 2-adrenoceptor.
S Uhlén et al.
British journal of pharmacology 106 (4), 986-95 (Aug 1992)
info:pmid/1356570
says that oxymetazoline and guanfacine are alpha2A selective over alpha2C, but doesn't mention alpha2B or alpha2B. maybe this is before they were discovered.
Posted by chris979 to oxymetazoline guanfacine alpha2 on Sun Jun 17 2007 at 03:32 UTC | info | related
 
The alpha-2a noradrenergic agonist, guanfacine, improves delayed response performance in young adult rhesus monkeys.
J S Franowicz and A F Arnsten
Psychopharmacology 136 (1), 8-14 (Mar 1998)
info:pmid/9537677
apparently says that guanfacine affects alpha2D
Posted by chris979 to guanfacine alpha2 on Sun Jun 17 2007 at 03:09 UTC | info | related
 
Medetomidine, atipamezole, and guanfacine in delayed response performance of aged monkeys.
P Rämä et al.
Pharmacology, biochemistry, and behavior 55 (3), 415-22 (Nov 1996)
info:pmid/8951983
"Clonidine and medetomidine are much less selective than guanfacine with respect to alpha-2A and alpha-2B receptor subtypes."
Posted by chris979 to guanfacine Clonidine alpha2 Dexmedetomidine on Sun Jun 17 2007 at 03:05 UTC | info | related
 
Testosterone Dependence of Salt-Induced Hypertension in Sabra Rats and Role of Renal alpha 2-Adrenoceptor Subtypes
Mostafa Khalid et al.
Journal of Pharmacology And Experimental Therapeutics 300 (1), 43-9 (01 Jan 2002)
info:doi/10.1124/jpet.300.1.43
Says that guanfacine is selective for alpha2A.
Posted by chris979 to guanfacine alpha2 on Sun Jun 17 2007 at 02:51 UTC | info | related
 
Role of serotonin and noradrenaline in stress urinary incontinence
MC Michel and SLM Peters
BJU International 94 (s1), 23-30 (2004)
info:doi/10.1111/j.1464-410X.2004.04811.x
Mentions alpha2 receptors, but says they're excitatory.
Posted by chris979 to alpha2 new unread review on Sun Apr 22 2007 at 05:30 UTC | info | related
 
Micturition in thoracic spinal cord injured cats with autografting of the adrenal medulla to the sacral spinal cord.
K Sugaya et al.
The Journal of urology 166 (6), 2525-9 (Dec 2001)
info:pmid/11696822
Mentions alpha2 receptors. Probably won't be any big breakthrough.
Posted by chris979 to alpha2 unread on Sun Apr 22 2007 at 05:29 UTC | info | related
 
Central nervous system control of the lower urinary tract: new pharmacological approaches to stress urinary incontinence in women.
Karl Thor and Craig Donatucci
The Journal of urology 172 (1), 27-33 (Jul 2004)
info:pmid/15201731 | info:doi/10.1097/01.ju.0000118381.04432.22
Talks about alpha2, apparently.
Posted by chris979 to alpha1 alpha2 new unread on Sun Apr 22 2007 at 05:12 UTC | info | related
 
New Approaches in the Treatment of Overactive Bladder: Targeting Adrenergic Receptors and Neurokinin Receptors
O Ishizuka
Current Medicinal Chemistry - Central Nervous System Agents
Posted by chris979 to alpha2 unread on Sun Apr 22 2007 at 05:08 UTC | info | related

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