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Rac downregulates Rho activity: reciprocal balance...[J Cell Biol. 1999] - PubMed Result

Rac downregulates Rho activity reciprocal balance between both GTPases determines cellular morphology and migratory behavior

E E Sander et al.

The Journal of cell biology 147 (5), 1009-22 (29 Nov 1999)

info:pmid/10579721

Posted by allesfliesst to Cdc42 Cross-talk Rho Rac on Mon Dec 03 2007 at 17:01 UTC | info | related

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways.

K Reif et al.

Current biology : CB. 6 (11), 1445-55 (01 Nov 1996)

info:pmid/8939609

Posted by allesfliesst and 1 other to Rho Rac p110 PI3K targeting membrane on Wed Nov 28 2007 at 14:03 UTC | info | related

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia.

C D Nobes and A Hall

Cell 81 (1), 53-62 (07 Apr 1995)

info:pmid/7536630

Posted by allesfliesst to filopodia lamellipodia fibers stress GTPasen GTPases Cdc42 Rac Rho on Wed Nov 28 2007 at 13:33 UTC | info | related

A molecular switch that controls cell spreading and retraction

Panagiotis Flevaris et al.

The Journal of Cell Biology 179 (3), 553-65 (05 Nov 2007)

info:doi/10.1083/jcb.200703185

Posted by allesfliesst to Src Rho integrins switch retraction spreading calpains on Fri Nov 23 2007 at 12:19 UTC | info | related

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

Gilles Gadea et al.

The Journal of cell biology 178 (1), 23-30 (02 Jul 2007)

info:pmid/17606864 | info:doi/10.1083/jcb.200701120

Posted by allesfliesst to invasion amoeboid migration ROCK Rho p53 on Tue Nov 20 2007 at 21:28 UTC | info | related

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis.

Erik Sahai and Christopher Marshall

Nature cell biology 5 (8), 711-9 (Aug 2003)

info:pmid/12844144 | info:doi/10.1038/ncb1019

Posted by allesfliesst to invasion tumor ROCK Rho mesenchymal migration amoeboid ezrin on Tue Nov 20 2007 at 21:24 UTC | info | related

FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling

Yasutaka Ohta, John Hartwig, and Thomas Stossel

Nat Cell Biol 8 (8), 803-14 (Aug 2006)

info:doi/10.1038/ncb1437

Posted by allesfliesst and 2 others to Filamin actin cortical Rho Blebbs Blebs ROCK GAP Rac filgap on Tue Nov 20 2007 at 15:24 UTC | info | related

Possible involvement of the inactivation of the Rho-Rho-kinase pathway in oncogenic Ras-induced transformation.

I Izawa et al.

Oncogene 17 (22), 2863-71 (03 Dec 1998)

info:pmid/9879992 | info:doi/10.1038/sj.onc.1202213

Posted by allesfliesst to Cross-talk transformation ras ROCK Rho on Sun Nov 18 2007 at 19:00 UTC | info | related

Oncogenic Ras leads to Rho activation by activating the mitogen-activated protein kinase pathway and decreasing Rho-GTPase-activating protein activity.

Jeffrey Chen et al.

The Journal of biological chemistry 278 (5), 2807-18 (31 Jan 2003)

info:pmid/12429740 | info:doi/10.1074/jbc.M207943200

Posted by allesfliesst to ROCK oncogenic Cross-talk Rho ras on Sun Nov 18 2007 at 17:08 UTC | info | related

Inhibition of myosin light chain kinase by p21-activated kinase.

L Sanders et al.

Science (New York, N.Y.) 283 (5410), 2083-5 (26 Mar 1999)

info:pmid/10092231

Posted by allesfliesst to Rho Rac Cross-talk myosin-II Pak on Sun Nov 18 2007 at 16:23 UTC | info | related

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