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Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42.

Soren Prag et al.

Molecular biology of the cell 18 (8), 2935-48 (Aug 2007)

info:pmid/17538024 | info:doi/10.1091/mbc.E06-11-1031

Posted by allesfliesst to Cdc42 GEF DBL ezrin on Sun Nov 18 2007 at 15:37 UTC | info | related

Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation.

Kent Rossman et al.

The Journal of biological chemistry 278 (20), 18393-18400 (16 May 2003)

info:pmid/12637522 | info:doi/10.1074/jbc.M300127200

Posted by allesfliesst to GEF GTPasen Rho signaling intramolecular DBL dh pH on Sat Nov 03 2007 at 12:54 UTC | info | related

Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.

C Russo et al.

The Journal of biological chemistry 276 (22), 19524-31 (01 Jun 2001)

info:pmid/11278560 | info:doi/10.1074/jbc.M009742200

Posted by allesfliesst to dh pH GEF intramolecular DBL Rho on Sat Nov 03 2007 at 12:49 UTC | info | related

Autoinhibition mechanism of proto-Dbl.

F Bi et al.

Molecular and cellular biology 21 (5), 1463-74 (Mar 2001)

info:pmid/11238883 | info:doi/10.1128/MCB.21.5.1463-1474.2001

Posted by allesfliesst to inhibition intramolecular pH dh DBL on Sat Nov 03 2007 at 12:39 UTC | info | related

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation.

B Aghazadeh et al.

Cell 102 (5), 625-33 (01 Sep 2000)

info:pmid/11007481

Posted by allesfliesst to structure vav inhibition dh DBL pH on Sat Nov 03 2007 at 12:33 UTC | info | related

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