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CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis.

S Radoja et al.

Journal of immunology (Baltimore, Md. : 1950) 167 (9), 5042-51 (01 Nov 2001)

info:pmid/11673513

Posted by AnyKine to perforin TIL on Fri Jul 28 2006 at 14:31 UTC | info | related

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