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Recent "topoisomerase" articles

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Modulation of drug sensitivity in yeast cells by the ATP-binding domain of human DNA topoisomerase IIalpha
Nathalie Vilain et al.
Posted by labkatja to Etoposide topoisomerase yeast drugs on Wed Jun 17 2009 at 12:12 UTC | info | related
 
Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models.
Paola Ulivi et al.
Neoplasia (New York, N.Y.) 7 (2), 152-61 (Feb 2005)
info:pmid/15802020 | info:doi/10.1593/neo.04397
Posted by ssaleh to topoisomerase bladder cancer on Tue Apr 07 2009 at 19:22 UTC | info | related
 
Chemical and traditional mutagenesis of vaccinia DNA topoisomerase provide insights to cleavage site recognition and transesterification chemistry.
Lyudmila Yakovleva et al.
The Journal of biological chemistry, (25 Mar 2008)
info:pmid/18367446 | info:doi/10.1074/jbc.M801595200
Posted by cupton to VBRC poxvirus topoisomerase on Mon Mar 31 2008 at 17:09 UTC | info | related
 
Targeting the Inverted CCAAT Box-2 of the Topoisomerase IIαGene: DNA Sequence Selective Recognition by a Polyamide-Intercalator as a Staggered Dimer
Bioorganic & Medicinal Chemistry, (2007)
info:doi/10.1016/j.bmc.2007.10.059
Posted by Papps to polyamide distamycin topoisomerase on Mon Feb 18 2008 at 01:56 UTC | info | related
 
Total Synthesis of the Topopyrones: A New Class of Topoisomerase I Poisons
The Journal of Organic Chemistry 73 (3), 785 (2008)
info:doi/10.1021/jo702487r
Posted by Papps to teaching topoisomerase on Mon Jan 28 2008 at 03:29 UTC | info | related
 
Topoisomerase I inhibitors: camptothecins and beyond
Nature Reviews Cancer 6 (10), 789 (2006)
info:doi/10.1038/nrc1977
Posted by Papps to Camptothecin teaching topoisomerase on Sun Aug 19 2007 at 07:37 UTC | info | related
 
Camptothecin, over four decades of surprising findings
Phytochemistry 65 (20), 2735 (2004)
info:doi/10.1016/j.phytochem.2004.09.001
Posted by Papps to Camptothecin teaching topoisomerase cancer on Sun Aug 19 2007 at 02:27 UTC | info | related
 
Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection
jac.oxfordjournals.org.ezproxy2.library.usyd.edu.au
Posted by Papps to quinolone gyrase antibiotics teaching topoisomerase on Sun Aug 19 2007 at 01:39 UTC | info | related
 
Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI
Kevin Corbett, Piero Benedetti, and James Berger
Nat Struct Mol Biol 14 (7), 611-9 (Jul 2007)
info:doi/10.1038/nsmb1264
Posted by janetgyang to njr II topoisomerase on Thu Aug 16 2007 at 05:06 UTC | info | related
 
Opinion: The crucible
www.rsc.org
DNA mechanics seems crucial, for example, to the tight packaging of genomic material inside viruses (where it seems poised like a wound spring for injection into infected cells), the folding-up of chromosomes, and the binding to DNA of proteins that regulate the readout of genetic information (transcription).
Posted by jsmoore to mechanical properties Nucleic Acids topoisomerase DNA drugs on Tue Aug 14 2007 at 01:20 UTC | info | related

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