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Recent "rapamycin" articles

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BBC NEWS | Health | Drug enhances power of vaccines - on article in Nature
news.bbc.co.uk
A common immunosuppressive drug may have the ability to boost the power of vaccines, research suggests. Rapamycin is commonly give to transplant patients to stop their bodies rejecting donor organs. In tests on mice and monkeys, scientists found it enhanced the response of their immune system to experimental vaccines.
 
Rapamycin decelerates cellular senescence.
Zoya Demidenko et al.
Cell cycle (Georgetown, Tex.) 8 (12), (01 Jun 2009)
"In human and rodent cell lines, rapamycin (an inhibitor of mTOR) dramatically decelerated loss of proliferative potential caused by ectopic p21, p16 and sodium butyrate-induced p21."
Posted by chrispatil to rapamycin senescence tor on Thu May 28 2009 at 17:06 UTC | info | related
 
Efficacy of Systemically Administered Oncolytic Vaccinia Virotherapy for Malignant Gliomas Is Enhanced by Combination Therapy with Rapamycin or Cyclophosphamide
Xue Qing Lun et al.
Clinical Cancer Research 15 (8), 2777-88 (15 Apr 2009)
inter cranial injection not good
 
DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses
Proceedings of the National Academy of Sciences, (2009)
Posted by scblackman to rapamycin mTOR hypoxia DJ-1 on Mon Jan 26 2009 at 18:18 UTC | info | related
 
Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid - a Competition with Rapamycin
Alfredo Toschi et al.
Molecular and Cellular Biology, MCB.00782-08 (29 Dec 2008)
 
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis.
Veronique Nogueira et al.
Cancer cell 14 (6), 458-70 (09 Dec 2008)
Rapamycin + ROS induction - the cure might be worse than the disease
 
Protein synthesis-dependent LTP in isolated dendri...[Hippocampus. 2005] - PubMed Result
www.ncbi.nlm.nih.gov
Posted by rapanui777 to rapamycin LTP on Mon Dec 01 2008 at 14:57 UTC | info | related
 
Induction and maintenance of late-phase long-term potentiation in isolated dendrites of rat hippocampal CA1 pyramidal neurones.
Catherine A Vickers, Kirsten S Dickson, and David J A Wyllie
The Journal of physiology 568 (Pt 3), 803-13 (01 Nov 2005)
Posted by rapanui777 to rapamycin LTP on Mon Dec 01 2008 at 14:55 UTC | info | related
 
The identification of an internal ribosomal entry site in the 5'-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage.
Posted by rapanui777 and 288 others with 20 comments to rapamycin IRES on Thu Nov 20 2008 at 14:08 UTC | info | related
 
4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implications.
Gemma Armengol et al.
Cancer research 67 (16), 7551-5 (15 Aug 2007)

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