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Recent "probability" articles

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PLoS Computational Biology: A Probabilistic Model of Local Sequence Alignment That Simplifies Statistical Significance Estimation
www.ploscompbiol.org
 
PLoS Computational Biology: Probabilistic Phylogenetic Inference with Insertions and Deletions
www.ploscompbiol.org
Posted by suja and 2 others to probability indel phylogeny on Wed Oct 15 2008 at 03:29 UTC | info | related
 
Neural correlates, computation and behavioural impact of decision confidence
Adam Kepecs et al.
Nature 455 (7210), 227-31 (11 Sep 2008)
 
Very good tutorial for Statistics
www.transwebtutors.com
Its a great resource for statistis, it includes vast range of topics including Diagrammatic Representation of Data, Graphic Representation of Data, Measures of Central Tendency, Measures of Dispersion , Exact Sampling Distributions (t, F and Z Distributions), Exact Sampling Distributions (Chi-Square Distribution), Multiple Regression and Correlation, Hypothesis Testing, Theory of Estimation etc.. Everything is explained with great detail.
 
eCodonOpt: a systematic computational framework for optimizing codon usage in directed evolution experiments
Gregory L Moore and Costas D Maranas
Nucleic acids research 30 (11), 2407-16 (01 Jun 2002)
 
Stochastic kinetics description of a simple transcription model
MR Roussel and R Zhu
Bulletin of mathematical biology 68 (7), 1681-1713 (01 Oct 2006)
Model of transcription with elongation. Every site can be: Unoccupied, Occupied, Activated (with NTP added). Analytical solution of ME for case without bumping. Approximate solution for statistically independent sites. Analogy to phase transition in traffic models. Order parameter -> average occupation of last 10 sites - plot. Weird: The promoter is freed after the new transcript is made (Eq. 4).
 
Interpretation of and preference for probability expressions among Japanese patients and physicians.
Motoki Ohnishi et al.
Family practice 19 (1), 7-11 (Feb 2002)
BACKGROUND: Patients and physicians often communicate using qualitative probability expressions that describe expected outcomes or risks of a medical intervention without knowing whether or not they share the same understanding. OBJECTIVE: The aim of the present study was to determine interpretations of qualitative probability expressions in clinical settings by Japanese patients and physicians as well as their assessments and preferences about physicians? use of such expressions. METHODS: One hundred and sixty-eight consecutive patients aged 16 years or older, who attended a university hospital during a 2-week period in 1999, and 156 physicians recruited through the Japanese General Medicine Research Network participated in this cross-sectional survey, using a self-administered questionnaire. Participants were asked to assign numerical interpretations as a percentage to 10 qualitative expressions of probability in two clinical situations related to prescribing a medicine for a cold and an anti-cancer drug. They were also asked which type of expression, qualitative or quantitative, they usually use when communicating probabilistic clinical information and which they prefer. RESULTS: The estimates of probability expressions showed wide variations, especially among patients. Patients tended to assign lower and higher values to highly positive and negative probability expressions, respectively, than physicians. Clinical context also influenced the estimation: both groups tended to assign higher estimates in the anti-cancer drug situation than in the cold treatment situation. Factor analysis revealed three psychologically meaningful factors in each situation. More patients than physicians (64.6% versus 50.3%) thought that physicians do not use numbers in routine practice. More than 20% of both patients and physicians considered that the actual use of qualitative terms by physicians is undesirable. Nevertheless, a sizable number of patients (41.4%) and physicians (15.2%) considered it preferable that physicians do not use numbers. CONCLUSION: Since interpretation of qualitative expressions of probability in Japanese is subject to large interpersonal variability and differences between patients and physicians, as well as context dependence, the use of qualitative expressions alone might cause misunderstanding among the parties involved. However, the majority of patients prefer words to numbers at present. Therefore, physicians, at least in Japan, ought to provide patients with both numbers and words when critical decisions need to be communicated.
Posted by familydoc to probability on Thu Apr 24 2008 at 03:44 UTC | info | related
 
High-resolution genetic mapping of complex traits
L Kruglyak and E S Lander
American journal of human genetics 56 (5), 1212-23 (May 1995)
 
Assessing the fraction of short-distance tandem splice sites under purifying selection.
Michael Hiller et al.
RNA (New York, N.Y.) 14 (4), 616-29 (11 Feb 2008)
 
A new stochastic model of episode peak and duration for eco-hydro-climatic applications
Ecological Modelling, (2007)

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