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Immunity -- Structural Mechanism of RNA Recognition by the RIG-I-like Receptors
www.immunity.com
Cytoplasmic nonself RNA, such as that generated by invading viruses, is recognized by a family of sensory molecules termed RIG-I-like Receptors (RLRs). Here, we discuss the mechanism of the RLRs' sensing of nonself RNA. Our findings define three functional domains of RLRs and provide insights into how RLRs function as a molecular switch through interactions with virus-specific RNA ligands.
Posted by NatureRevMicrobiol to RNA inflammation immunity innate viruses RIG-I on Sun Aug 17 2008 at 02:29 UTC | info | related
 
Innate immune modulation by RNA viruses
www.nature.com
Posted by rnai25git to immunity innate on Tue Aug 12 2008 at 20:47 UTC | info | related
 
Novel genes dramatically alter regulatory network topology in amphioxus
Qing Zhang et al.
Genome Biology 9 (8), R123 (04 Aug 2008)
info:doi/10.1186/gb-2008-9-8-r123
Posted by hofmannk to immunity innate on Tue Aug 05 2008 at 09:06 UTC | info | related
 
Bacterial lipopolysaccharides induce genes involved in the innate immune response in embryos of the zebrafish (Danio rerio).
Joerg Watzke, Kristin Schirmer, and Stefan Scholz
Fish & shellfish immunology 23 (4), 901-5 (Oct 2007)
info:pmid/17442590 | info:doi/10.1016/j.fsi.2007.03.004
Posted by cmorton to embryo innate LPS zebrafish on Mon Jun 30 2008 at 13:48 UTC | info | related
 
Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish.
Cornelia Stein et al.
Genome biology 8 (11), R251 (2007)
info:pmid/18039395 | info:doi/10.1186/gb-2007-8-11-r251
Posted by cmorton to Immune system innate zebrafish on Mon Jun 30 2008 at 13:24 UTC | info | related
 
IMMUNOLOGY: The Right Resident Bugs
Neal Silverman and Nicholas Paquette
Science 319 (5864), 734-5 (08 Feb 2008)
info:doi/10.1126/science.1154209
A link between a transcription factor and control of immune responses in the fly gut opens the door to analyses of host-microbe mutalism.
Posted by NatureRevMicrobiol to microbiota intestines immunity innate Drosophila on Sun Feb 10 2008 at 01:30 UTC | info | related
 
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
Miguel Sanjuan et al.
Nature 450 (7173), 1253-7 (20 Dec 2007)
info:doi/10.1038/nature06421
Posted by res2003 and 2 others to immunity innate Macrophage on Wed Dec 19 2007 at 23:11 UTC | info | related
 
Innate immunity and its evasion and suppression by hymenopteran endoparasitoids
Otto Schmidt, Uli Theopold, and Mike Strand
BioEssays 23 (4), 344-51 (2001)
info:doi/10.1002/bies.1049
Posted by Ian_York to Invertebrate innate polydnavirus on Wed Dec 05 2007 at 17:23 UTC | info | related
 
How to kill a mocking bug?
Vitor Pinheiro and David Ellar
Cellular Microbiology 8 (4), 545-57
info:doi/10.1111/j.1462-5822.2006.00693.x
Posted by Ian_York to innate evolution on Thu Nov 29 2007 at 21:07 UTC | info | related
 
Urochordates and the origin of natural killer cells: Identification of a CD94/NKR-P1-related receptor in blood cells of Botryllus
Konstantin Khalturin et al.
Proceedings of the National Academy of Sciences 100 (2), 622-7 (21 Jan 2003)
info:doi/10.1073/pnas.0234104100
Posted by Ian_York to innate evolution on Thu Nov 29 2007 at 21:05 UTC | info | related

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