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Interfering with disease: a progress report on siRNA-based therapeutics
Antonin De Fougerolles et al.
Nat Rev Drug Discov 6 (6), 443-53 (Jun 2007)
info:doi/10.1038/nrd2310
Posted by nazzareno and 3 others with 1 comment to drugdiscovery siRNA on Sun Jun 10 2007 at 17:51 UTC | info | related
 
PTC124 targets genetic disorders caused by nonsense mutations
Ellen Welch et al.
Nature 447 (7140), 87-91 (03 May 2007)
info:doi/10.1038/nature05756
Posted by nazzareno and 1 other to drugdiscovery companies on Sun Jun 10 2007 at 17:46 UTC | info | related
 
Illuminating drug discovery with biological pathways.
G Apic et al.
FEBS Lett 579 (8), 1872-7 (21 Mar 2005)
Posted by kuhn to drugdiscovery SystemsBiology Drug pathways on Mon May 29 2006 at 07:15 UTC | info | related
 
What do we learn from high-throughput protein interaction data?
Expert Review of Proteomics 1 (1), 111 (2004)
info:doi/10.1586/14789450.1.1.111
Posted by kuhn to drugdiscovery interaction networks Protein on Mon May 29 2006 at 07:15 UTC | info | related
 
A Pharmacological Map of the PI3-K Family Defines a Role for p110alpha in Insulin Signaling.
Zachary A Knight et al.
Cell. 125 (4), 733-47 (26 Apr 2006)
info:pmid/16647110 | info:doi/10.1016/j.cell.2006.03.035
Posted by kuhn and 3 others with 1 comment to drugdiscovery similarity on Mon May 29 2006 at 07:15 UTC | info | related
 
Innovation: Can cell systems biology rescue drug discovery?
Can cell systems biology rescue drug discovery
Eugene C Butcher
Nature reviews. Drug discovery. 4 (6), 461-7 (Jun 2005)
info:pmid/15915152 | info:doi/10.1038/nrd1754
Posted by kuhn and 2 others to systems_biology drugdiscovery on Mon Mar 06 2006 at 14:41 UTC | info | related
 
Pharmaceuticals: A new grammar for drug discovery
Mark Fishman and Jeffery Porter
Nature 437 (7058), 491-3 (22 Sep 2005)
info:doi/10.1038/437491a
Posted by kuhn and 2 others to drugdiscovery on Mon Mar 06 2006 at 14:41 UTC | info | related
 
Illuminating drug discovery with biological pathways.
Gordana Apic et al.
FEBS letters. 579 (8), 1872-7 (21 Mar 2005)
info:pmid/15763566 | info:doi/10.1016/j.febslet.2005.02.023
Posted by kuhn and 1 other to systems_biology pathways Drug drugdiscovery on Mon Mar 06 2006 at 14:41 UTC | info | related
 
Can we rationally design promiscuous drugs?
Andrew Hopkins, Jonathan Mason, and John Overington
Curr Opin Struct Biol, (24 Jan 2006)
Posted by kuhn to promiscuity Drug drugdiscovery on Mon Mar 06 2006 at 14:41 UTC | info | related
 
Drug discovery: a historical perspective.
Drug Discovery A Historical Perspective
Science 287 (5460), 1960 (2000)
info:doi/10.1126/science.287.5460.1960
Posted by kuhn to history drugdiscovery on Mon Mar 06 2006 at 14:41 UTC | info | related

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