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The New England Journal of Medicine 361 (1), 40-51 (02 Jul 2009)
www.liebertonline.com
article in 2009 cgm issue of Diabetes Technology & Therapeutics
www.healthmate.blogspot.com
http://healthmate.blogspot.com is an informative blog that provides exciting information on health care. You can find surprising information about alcohol, diabetes, or even the latest information about signs and prevention of the pandemic swine flue.
www.liebertonline.com
2009 update on artificial pancreas
The British Journal of Diabetes & Vascular Disease 9 (3), (01 May 2009)
see figure 2.DM pts to investigate for silent IHD :ED+PVD+abnormal resting ECG+postural BP drop as sign cardiac autnomic neuropathy+unexplained SOBOE.consider 24 hr ECG looking ST depression 1mm or more >1 min
Annals of Internal Medicine, 0000605-200906020-00118 (20 Apr 2009)
Online Ann Intern Med editorial
Journal of Biological Chemistry 284 (27), 17947-55 (03 Jul 2009)
"Diabetes mellitus accelerates cardiovascular microangiopathies and atherosclerosis, which are a consequence of hyperglycemia. The aldose reductase (AR) polyol pathway contributes to these microvascular complications, but how it mediates vascular damage in response to hyperglycemia is less understood. The RUNX2 transcription factor, which is repressed in diabetic animals, promotes vascular endothelial cell (EC) migration, proliferation, and angiogenesis. Here we show that physiological levels of glucose (euglycemia) increase RUNX2 DNA binding and transcriptional activity, whereas hyperglycemia does not"
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