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Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
Sylvia Fischer et al.
Nature 455 (7212), 491-6 (25 Sep 2008)
info:doi/10.1038/nature07274
The first example in C. elegans of a gene product that results from trans-splicing of two nearby genes. This will cause database annotators a lot of trouble. One gene or two?
Posted by kbradnam to chimera Trans-Splicing C. elegans splicing on Thu Sep 25 2008 at 17:50 UTC | info | related
 
EF-G-independent reactivity of a pre-translocation-state ribosome complex with the aminoacyl tRNA substrate puromycin supports an intermediate (hybrid) state of tRNA binding
Divya Sharma, Daniel R Southworth, and Rachel Green
RNA (New York, N.Y.) 10 (1), 102-13 (Jan 2004)
info:pmid/14681589
Posted by gjwilliams2 to Translocation, Genetic RNA, Transfer, Met RNA, Transfer, Amino Acyl Peptide Chain Elongation, Translational Research Support, Non-U.S. Gov't Mutagenesis, Site-Directed RNA, Messenger Trypanocidal Agents Peptide Elongation Factor G Peptidyl Transferases Puromycin chimera Protein Biosynthesis Ribosomes Escherichia coli COMPARATIVE STUDY kinetics metabolism genetics mutation on Thu Jul 03 2008 at 00:50 UTC | info | related
 
Enhanced degradation of polychlorinated biphenyls by directed evolution of biphenyl dioxygenase
Tetsuya Kumamaru et al.
Nature biotechnology 16 (7), 663-6 (Jul 1998)
info:pmid/9661201 | info:doi/10.1038/nbt0798-663
Posted by gjwilliams2 to Research Support, Non-U.S. Gov't polychlorinated biphenyls oxygenases Iron-Sulfur Proteins chimera Pseudomonas Substrate Specificity Molecular Sequence Data Amino Acid Sequence polymerase chain reaction biodegradation Escherichia coli Burkholderia cepacia metabolism genetics chemistry on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling
Fred Christians et al.
Nature biotechnology 17 (3), 259-64 (Mar 1999)
info:pmid/10096293 | info:doi/10.1038/7003
Posted by gjwilliams2 to Herpesvirus 2, Human Herpesvirus 1, Human Models, Molecular Dose-Response Relationship, Drug Cloning, Molecular Sequence Homology, Amino Acid Thymidine Kinase zidovudine chimera therapeutic use drug effects Enzymology hydrogen bonding Molecular Sequence Data Amino Acid Sequence mutagenesis Computer Simulation Escherichia coli COMPARATIVE STUDY cell division humans Pharmacology methods kinetics metabolism genetics on Wed Jul 02 2008 at 23:28 UTC | info | related
 
Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells
J A Piedrahita et al.
Proceedings of the National Academy of Sciences of the United States of America 89 (10), 4471-5 (15 May 1992)
info:pmid/1584779
Posted by ranicruz to Zmpste24 Research Support, U.S. Gov't, P.H.S. Blotting, Southern Mice, Mutant Strains Recombination, Genetic Apolipoproteins E lipodystrophy chimera Restriction Mapping Plasmids Oligodeoxyribonucleotides Base Sequence isolation & purification Cell Line Molecular Sequence Data polymerase chain reaction apoE methods HAART embryo animals mice HIV genetics DNA AIDS Stem Cells physiology on Tue Jun 10 2008 at 17:59 UTC | info | related
 
Interspecific hybrid ancestry of a plant adaptive radiation: allopolyploidy of the Hawaiian silversword alliance (Asteraceae) inferred from floral homeotic gene duplications
M Barrier et al.
Molecular biology and evolution 16 (8), 1105-13 (Aug 1999)
info:pmid/10474905
Posted by rounsley to Adaptation, Physiological Evolution, Molecular MADS Domain Proteins Gene Dosage founder effect chimera radiation effects Arabidopsis Proteins Species Specificity Plant Proteins Homeodomain Proteins polyploidy Molecular Sequence Data Amino Acid Sequence Hawaii gene duplication North America polymerase chain reaction Asteraceae genetics phylogeny none on Fri May 30 2008 at 22:43 UTC | info | related
 
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
James O et al.
Nature biotechnology., published online 25 Jun 2006
info:pmid/16823371 | info:doi/10.1038/nbt1223
Posted by ekoteng and 2 others to aptamer chimera on Sun Dec 02 2007 at 21:46 UTC | info | related
 
Humanization of an anti-human TNF-α antibody by variable region resurfacing with the aid of molecular modeling
Humanization of an antihuman TNFalpha antibody by variable region resurfacing with the aid of molecular modeling
Molecular Immunology 42 (12), 1445 (2005)
info:doi/10.1016/j.molimm.2005.01.015
Design of a humanized version of the murine anti-TNF-alpha antibody Z12.
Posted by tupeliano to In Silico Mutagenesis chimera modeling antibodies on Wed Feb 14 2007 at 06:20 UTC | info | related
 
Excision and insertion of the conjugative transposon Tn916 involves a novel recombination mechanism
M G Caparon and J R Scott
Cell 59 (6), 1027-34 (22 Dec 1989)
info:pmid/2557157
DA - 19900207 IS - 0092-8674 (Print) LA - eng PT - Journal Article RN - 0 (DNA Transposable Elements) RN - 0 (DNA, Bacterial) RN - 0 (DNA, Circular) RN - 0 (Nucleic Acid Heteroduplexes) SB - IM
Posted by ndhoang to Nucleic Acid Heteroduplexes chimera DNA Transposable Elements Base Composition Plasmids Nucleic Acid Hybridization Base Sequence Conjugation Molecular Sequence Data Southern Escherichia coli P.H.S. U.S.Gov't Research Support Movement microbiology bacterial Circular blotting Molecular Recombination genetic genetics DNA immunology cloning on Wed Jan 10 2007 at 09:07 UTC | info | related
 
Protoplast transformation in coryneform bacteria and introduction of an alpha-amylase gene from Bacillus amyloliquefaciens into Brevibacterium lactofermentum
Protoplast transformation in coryneform bacteria and introduction of an alphaamylase gene from Bacillus amyloliquefaciens into Brevibacterium lactofermentum
M D Smith et al.
Applied and environmental microbiology 51 (3), 634-9 (Mar 1986)
info:pmid/3008649
DA - 19860505 IS - 0099-2240 (Print) LA - eng PT - Journal Article RN - EC 3.1.21 (DNA Restriction Enzymes) RN - EC 3.2.1.1 (alpha-Amylase) RN - EC 3.2.1.17 (Muramidase) SB - IM
Posted by ndhoang to Brevibacterium Protoplasts alpha-Amylase Corynebacterium chimera DNA Restriction Enzymes Plasmids Muramidase Bacillus subtilis drug effects Enzymology transfection antibodies enzymes Pharmacology bacterial plasmid transformation bacteria Bacillus Genes genetics DNA on Wed Jan 10 2007 at 09:07 UTC | info | related

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