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Science at Ventedoy
www.ventedoy.com
Posted by ferat to reactions chemical on Thu Jul 03 2008 at 19:01 UTC | info | related
 
Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli
N Wymer et al.
Structure (London, England : 1993) 9 (1), 1-9 (10 Jan 2001)
info:pmid/11342129
Posted by gjwilliams2 to Aldehyde-Lyases Site-Directed Catalytic Domain Catalysis Lysine Gene Library secondary Substrate Specificity Matrix-Assisted Laser Desorption-Ionization Enzymology crystallography U.S. Gov't mass mutagenesis Non-U.S. Gov't Escherichia coli spectrometry P.H.S. Research Support binding sites chemical Molecular Models kinetics metabolism X-ray protein structure mutation chemistry on Thu Jul 03 2008 at 01:10 UTC | info | related
 
Expanding the structural and functional diversity of RNA: analog uridine triphosphates as candidates for in vitro selection of nucleic acids
N K Vaish et al.
Nucleic acids research 28 (17), 3316-22 (01 Sep 2000)
info:pmid/10954600
Posted by gjwilliams2 to Ribonuclease H, Calf Thymus Research Support, U.S. Gov't, Non-P.H.S. Templates, Genetic Uridine Triphosphate Chromatography, High Pressure Liquid Transcription, Genetic Uridine RNA-Directed DNA Polymerase DNA-Directed RNA Polymerases Viral Proteins Substrate Specificity analogs & derivatives Base Sequence Molecular Sequence Data BIOSYNTHESIS chemical kinetics metabolism RNA synthesis genetics chemistry on Thu Jul 03 2008 at 01:10 UTC | info | related
 
Inversion of the anomeric configuration of the transferred sugar during inactivation of the macrolide antibiotic oleandomycin catalyzed by a macrolide glycosyltransferase
L M Quirós, R J Carbajo, and J A Salas
FEBS letters 476 (3), 186-9 (07 Jul 2000)
info:pmid/10913610
Posted by gjwilliams2 to Streptomyces antibioticus Oleandomycin Glucosyltransferases Carbohydrate Conformation Anti-Bacterial Agents antagonists & inhibitors Sequence Homology Enzymology Amino Acid Sequence Magnetic Resonance Spectroscopy Amino Acid glycosylation Non-U.S. Gov't glucose Research Support chemical Models metabolism genetics chemistry on Thu Jul 03 2008 at 00:15 UTC | info | related
 
CloQ, a prenyltransferase involved in clorobiocin biosynthesis
Florence Pojer et al.
Proceedings of the National Academy of Sciences of the United States of America 100 (5), 2316-21 (04 Mar 2003)
info:pmid/12618544 | info:doi/10.1073/pnas.0337708100
Posted by gjwilliams2 to Dimethylallyltranstransferase Coumarins Novobiocin Gene Deletion Anti-Bacterial Agents Substrate Specificity analogs & derivatives Tyrosine Spectrum Analysis Molecular Sequence Data High Pressure Liquid Enzyme Inhibitors mass BIOSYNTHESIS Non-U.S. Gov't Time Factors Southern Escherichia coli Research Support Pharmacology chemical Streptomyces blotting Models kinetics metabolism Chromatography DNA mutation chemistry on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX
D G McCafferty, I A Lessard, and C T Walsh
Biochemistry 36 (34), 10498-10505 (26 Aug 1997)
info:pmid/9265630 | info:doi/10.1021/bi970543u
Posted by gjwilliams2 to Serine-Type D-Ala-D-Ala Carboxypeptidase Dipeptidases Enterococcus ATP-Binding Cassette Transporters thermolysin Thrombin DNA Mutational Analysis Site-Directed Escherichia coli Proteins Conserved Sequence Carrier Proteins Monosaccharide Transport Proteins Recombinant Fusion Proteins Bacterial Proteins Sequence Alignment isolation & purification Enzymology zinc Molecular Sequence Data Amino Acid Sequence Protein Conformation U.S. Gov't mutagenesis Non-U.S. Gov't Escherichia coli P.H.S. Research Support binding sites chemical Models kinetics circular dichroism metabolism genetics chemistry on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Evidence for a glutathionyl-enzyme intermediate in the amidase activity of the bifunctional glutathionylspermidine synthetase/amidase from Escherichia coli
C H Lin et al.
Biochemistry 36 (48), 14930-8 (02 Dec 1997)
info:pmid/9398217 | info:doi/10.1021/bi9714464
Posted by gjwilliams2 to Flow Injection Analysis Amide Synthases Iodoacetamide Enzyme Activation Amidohydrolases antagonists & inhibitors Multienzyme Complexes Recombinant Proteins analogs & derivatives Acylation Peptide Fragments Enzymology glutathione U.S. Gov't mutagenesis Escherichia coli P.H.S. Research Support Pharmacology binding sites chemical Models metabolism genetics on Thu Jul 03 2008 at 00:15 UTC | info | related
 
(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB)
W J Lees et al.
Biochemistry 35 (5), 1342-51 (06 Feb 1996)
info:pmid/8634262 | info:doi/10.1021/bi952287w
Posted by gjwilliams2 to Uridine Diphosphate N-Acetylglucosamine Deuterium Oxide Carbohydrate Dehydrogenases Stereoisomerism NADP Molecular Probes analogs & derivatives Oxidation-Reduction crystallography U.S. Gov't Non-U.S. Gov't P.H.S. Research Support binding sites chemical Molecular Models metabolism X-ray chemistry on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Biomimetic synthesis and optimization of cyclic peptide antibiotics
Rahul Kohli, Christopher Walsh, and Michael Burkart
Nature 418 (6898), 658-61 (08 Aug 2002)
info:pmid/12167866 | info:doi/10.1038/nature00907
Posted by gjwilliams2 to Tyrocidine Cyclic Cyclization Thiolester Hydrolases Biological Products Catalysis Anti-Bacterial Agents Microbial Sensitivity Tests Molecular Mimicry Substrate Specificity analogs & derivatives drug effects Peptides Molecular Sequence Data Hydrolysis Amino Acid Sequence erythrocytes U.S. Gov't BIOSYNTHESIS humans P.H.S. Research Support Pharmacology chemical metabolism synthesis chemical synthesis bacteria on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Vancomycin assembly: nature's way
Brian K Hubbard and Christopher T Walsh
Angewandte Chemie (International ed. in English) 42 (7), 730-65 (17 Feb 2003)
info:pmid/12596194 | info:doi/10.1002/anie.200390202
Posted by gjwilliams2 to Anti-Bacterial Agents Vancomycin Gene Expression Regulation drug effects glycosylation BIOSYNTHESIS Pharmacology bacterial Drug resistance chemical metabolism synthesis chemical synthesis bacteria genetics chemistry on Thu Jul 03 2008 at 00:15 UTC | info | related

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