Users who used antibodies:
Free online reference management for clinicians and scientists
Recent "antibodies" articles
- These articles and links have been posted by Connotea users using the tag "antibodies".
- To add to this collection, or to start your own library:
Watch a short video (2m 41s)
Create a Connotea Community Page about this tag. 

Number of articles per page:
Cancer Information & Education, (21 Jul 2008)
The chemist Dario Neri has carried out research for more than 15 years to find antibodies suitable as drug delivery vehicles for selective anti-cancer treatment.
www.immunity.com
Inflammation mediated by antibody-antigen complexes contributes to autoimmune diseases. Mice deficient in the common Fcγ-chain are protected from IgG-mediated glomerulonephritis and the reverse passive Arthus (RPA) reaction and FcR-bearing macrophages, and mast cells have been assigned primary roles in these processes. Here we demonstrate that neutrophil-selective transgenic expression of the two uniquely human neutrophil Fc gamma receptors (FcγRs), FcγRIIA and FcγRIIIB, in Fcγ-chain-deficient mice restored susceptibility to progressive glomerulonephritis and the cutaneous RPA reaction. FcγRIIIB and FcγRIIA mediated neutrophil accumulation, whereas FcγRIIA alone promoted organ injury. In a model of soluble immune complexes deposited within the vasculature, FcγRIIIB was responsible for neutrophil slow rolling and adhesion whereas in the cremaster RPA, induced by both vascular and tissue soluble immune complexes, FcγRIIA predominated. Thus, human FcγRs on neutrophils serve as molecular links between antibody and immunological disease, with FcγRIIA promoting tissue injury and FcγRIIIB and FcγRIIA displaying specialized context-dependent functions in neutrophil recruitment.
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
PLoS Medicine 2 (1), e17 (01 Jan 2005)
Proceedings of the National Academy of Sciences of the United States of America 100 (3), 856-61 (04 Feb 2003)
Chemistry & biology. 9 (8), 933-42 (Aug 2002)
Proceedings of the National Academy of Sciences of the United States of America 95 (25), 14590-1 (08 Dec 1998)
Science (New York, N.Y.) 240 (4851), 426-33 (22 Apr 1988)
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 332 (1263), 157-64 (29 May 1991)
Science (New York, N.Y.) 279 (5358), 1929-33 (20 Mar 1998)
<< Prev 0 Showing entries 1 to 10 of 357 total Next 10 >>



