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Recent "ageing" articles

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Sirtuins |[mdash]| novel therapeutic targets to treat age-associated diseases
Olivier Boss
Posted by molloyc to sirtuin ageing on Wed Oct 01 2008 at 15:07 UTC | info | related
 
Heart of Ageing Enzyme Revealed
www.nature.com
 
Genetic pathways that regulate ageing in model organisms: Nature
Genetic pathways that regulate ageing in model organisms
Leonard Guarente and Cynthia Kenyon
Nature 408 (6809), 255-62 (09 Nov 2000)
Posted by smithca2 and 1 other to ageing on Tue Jul 01 2008 at 22:00 UTC | info | related
 
Living on a break: cellular senescence as a DNA-damage response
Fabrizio D'Adda
Nat Rev Cancer 8 (7), 512-22 (Jul 2008)
Posted by s9753195 to senescence ageing cancer on Tue Jun 24 2008 at 12:52 UTC | info | related
 
From the Cover: Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita
Tom Vulliamy et al.
Proceedings of the National Academy of Sciences 105 (23), 8073-8 (10 Jun 2008)
Posted by bpatay to NHP@ telomeres ageing on Tue Jun 10 2008 at 19:38 UTC | info | related
 
Third age usability and safety--an ergonomics contribution to design
DAVID HITCHCOCK et al.
International Journal of Human-Computer Studies 55 (4), 635-43 (Oct 2001)
Commercial pressures are placing demands on the designer to provide solutions which are fit for purpose for all user groups. The needs of these groups can vary significantly yet inclusive design of mainstream products and work equipment remains a top priority. This paper is not an academic review of current theories of inclusive design methodologies. Rather, it explores the ergonomics contribution to the design process, the pitfalls to be avoided and suggests ways of avoiding them. Specifically, the needs of the Third Age are considered with their increasingly important requirements within the workplace and beyond. The authors contest that a user-centred approach is at the heart of achieving inclusive design; expecting the designer to apply ergonomics data without understanding user needs is unlikely to yield fit-for-purpose products.
 
A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells.
Rebecca H Cho, Hans B Sieburg, and Christa E Muller-Sieburg
Blood, (15 Apr 2008)
 
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing.
Paola Scaffidi and Tom Misteli
Nature cell biology, (02 Mar 2008)
 
Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates.
A F Arnsten and P S Goldman-Rakic
Science (New York, N.Y.) 230 (4731), 1273-6 (13 Dec 1985)
Posted by butterchicken to PFC ageing on Fri Feb 29 2008 at 11:47 UTC | info | related
 
A systematic look at an old problem
Thomas Kirkwood
Nature 451 (7179), 644-7 (07 Feb 2008)
Posted by JessBuxton and 1 other to ageing on Thu Feb 07 2008 at 10:14 UTC | info | related

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