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Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells.
Christopher M Snyder et al.
Immunity 29 (4), 650-9 (Oct 2008)
info:pmid/18957267 | info:doi/10.1016/j.immuni.2008.07.017
short bursts of prolif derived from memory cells MUST READ
Posted by stephr to CMV Tmem CD8 chronic on Mon Jan 05 2009 at 04:17 UTC | info | related
 
Stimulation History Dictates Memory CD8 T Cell Phenotype: Implications for Prime-Boost Vaccination
David Masopust et al.
The Journal of Immunology 177 (2), 831-9 (15 Jul 2006)
like Jabbari, boost
Posted by stephr to secondary Tmem LCMV CD8 on Thu Nov 27 2008 at 14:29 UTC | info | related
 
Understanding the generation and function of memory T cell subsets
Current Opinion in Immunology 17 (3), 326 (2005)
info:doi/10.1016/j.coi.2005.04.010
Sallusto and Lanzavecchia's short review. There's a long one too
Posted by stephr to TCM TEM Tmem review on Wed Nov 26 2008 at 17:15 UTC | info | related
 
Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression
Journal of Virology 81 (6), 2545 (2007)
info:doi/10.1128/jvi.02021-06
Arash Grakoui!
Posted by stephr to PD1 Tmem CD8 HCV chronic on Tue Nov 25 2008 at 15:35 UTC | info | related
 
The Role of Interleukin (IL)-10 in the Persistence of Leishmania major in the Skin after Healing and the Therapeutic Potential of Anti-IL-10 Receptor Antibody for Sterile Cure
Journal of Experimental Medicine 194 (10), 1497 (2001)
info:doi/10.1084/jem.194.10.1497
actual first Belkaid IL-10
Posted by stephr to IL-10 Tmem Treg Leishmania CD4 chronic on Tue Nov 25 2008 at 15:01 UTC | info | related
 
Immune Elimination of Leishmania major in Mice: Implications for Immune Memory, Vaccination, and Reactivation Disease
Jude E. Uzonna et al.
The Journal of Immunology 167 (12), 6967-74 (15 Dec 2001)
cited in Zaph as orig get rid of Leishmania, destroy immunity also sets up dose model that gets amazing titration of IL4vgamma
Posted by stephr to Tmem Leishmania CD4 chronic on Tue Nov 25 2008 at 14:51 UTC | info | related
 
Efficient Development of <i>Plasmodium</i> Liver Stage–Specific Memory CD8<sup>+</sup> T Cells during the Course of Blood‐Stage Malarial Infection
The Journal of Infectious Diseases 196 (12), 1827 (2007)
info:doi/10.1086/522965
simple- irradiated spz are (almost) as good as live spz at inducing and maintaining Tg mem-so blood stage doesn't interfere...
Posted by stephr to Zavala Tmem CD8 mouse malaria on Mon Nov 24 2008 at 19:14 UTC | info | related
 
Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria
Proceedings of the National Academy of Sciences 105 (37), 14017 (2008)
info:doi/10.1073/pnas.0805452105
nice paper, but doesn't cite Fidel at all, even though they have three papers with similar message-Hafalla JID, JI
Posted by stephr to Harty Tmem CD8 mouse malaria on Mon Nov 24 2008 at 19:12 UTC | info | related
 
Protracted Sterile Protection with <i>Plasmodium yoelii</i> Pre-erythrocytic Genetically Attenuated Parasite Malaria Vaccines Is Independent of Significant Liver-Stage Persistence and Is Mediated by CD8<sup>+</sup> T Cells
The Journal of Infectious Diseases 196 (4), 608 (2007)
info:doi/10.1086/519742
Posted by stephr to Kappe Tmem mouse vaccine malaria on Mon Nov 24 2008 at 16:59 UTC | info | related
 
Memory Generation and Maintenance of CD8+ T Cell Function during Viral Persistence
Stephanie S. Cush et al.
The Journal of Immunology 179 (1), 141-53 (01 Jul 2007)
great! gamma-herpes virus, cited in Nature Med Bustamente Tarleton no. 9
Posted by stephr to TCM TEM Tmem CD8 chronic on Fri Nov 21 2008 at 19:28 UTC | info | related

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