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Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution
Tuck Seng Wong et al.
Nucleic acids research 32 (3), e26 (2004)
info:pmid/14872057 | info:doi/10.1093/nar/gnh028
Posted by gjwilliams2 to Thionucleotides Sequence Deletion Research Support, Non-U.S. Gov't Point Mutation Mutagenesis, Insertional mutagenesis Luminescent Proteins analogs & derivatives Inosine Green Fluorescent Proteins methods Directed Molecular Evolution Deoxyadenine Nucleotides genetics DNA on Thu Jul 03 2008 at 01:10 UTC | info | related
 
Stereochemical course of catalysis by the Tetrahymena ribozyme
J Rajagopal, J A Doudna, and J W Szostak
Science (New York, N.Y.) 244 (4905), 692-4 (12 May 1989)
info:pmid/2470151
Posted by gjwilliams2 to Thionucleotides genetics Tetrahymena Templates, Genetic Enzymology T-Phages structure-activity relationship Ribonucleases Research Support, Non-U.S. Gov't RNA, Ribosomal RNA, Catalytic RNA Splicing RNA Precursors chemical synthesis RNA phosphorus oligonucleotides Molecular Conformation Introns Guanosine Exons metabolism DNA-Directed RNA Polymerases Catalysis animals on Thu Jul 03 2008 at 00:15 UTC | info | related
 
In vitro evolution of new ribozymes with polynucleotide kinase activity
J R Lorsch and J W Szostak
Nature 371 (6492), 31-6 (01 Sep 1994)
info:pmid/7521014 | info:doi/10.1038/371031a0
Posted by gjwilliams2 to Thionucleotides Selection (Genetics) Research Support, U.S. Gov't, P.H.S. Research Support, Non-U.S. Gov't RNA, Catalytic RNA classification Polynucleotide 5'-Hydroxyl-Kinase Nucleic Acid Conformation Molecular Sequence Data kinetics In Vitro evolution Cloning, Molecular Catalysis Base Sequence Aspergillus Nuclease S1 metabolism analogs & derivatives Adenosine Triphosphate on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution
Farid J Ghadessy et al.
Nature biotechnology 22 (6), 755-9 (Jun 2004)
info:pmid/15156154 | info:doi/10.1038/nbt974
Posted by gjwilliams2 to Thionucleotides Taq Polymerase Substrate Specificity Sequence Analysis, DNA Rhodamines Research Support, U.S. Gov't, P.H.S. Pyrimidine Dimers polymerase chain reaction Point Mutation mutation Models, Molecular microarray analysis kinetics Indoles Fluorescein-5-isothiocyanate methods Directed Molecular Evolution Deoxyuracil Nucleotides Deoxyribose Deoxyguanine Nucleotides metabolism Deoxyadenine Nucleotides chemical synthesis DNA Probes DNA Mutational Analysis DNA chemistry biotin genetics Base Pair Mismatch on Wed Jul 02 2008 at 23:28 UTC | info | related

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