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A new strategy for the synthesis of glycoproteins
Zhiwen Zhang et al.
Science (New York, N.Y.) 303 (5656), 371-3 (16 Jan 2004)
info:pmid/14726590 | info:doi/10.1126/science.1089509
Posted by gjwilliams2 to Uridine Diphosphate Galactose Tyrosine-tRNA Ligase Suppression, Genetic Serine Research Support, U.S. Gov't, P.H.S. Research Support, U.S. Gov't, Non-P.H.S. RNA, Transfer, Tyr Protein Processing, Post-Translational Protein engineering Myoglobin mutation Lectins glycosylation chemistry BIOSYNTHESIS Glycoproteins genetics Escherichia coli Directed Molecular Evolution Codon metabolism Acetylglucosamine acetylation on Thu Jul 03 2008 at 01:10 UTC | info | related
 
Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck
D G Winkler et al.
Proceedings of the National Academy of Sciences of the United States of America 90 (11), 5176-80 (01 Jun 1993)
info:pmid/8506364
Posted by gjwilliams2 to Threonine Pharmacology Tetradecanoylphorbol Acetate Serine P.H.S. U.S. Gov't Non-U.S. Gov't Research Support Recombinant Proteins Recombinant Fusion Proteins Protein-Tyrosine Kinase Phosphoserine Phosphorylation Phosphopeptides chemical synthesis Peptides Peptide Mapping Site-Directed mutagenesis Molecular Weight Molecular Sequence Data Lymphocyte Specific Protein Tyrosine Kinase p56(lck) humans Hela Cells metabolism isolation & purification genetics Glutathione Transferase Polyacrylamide Gel Two-Dimensional gel Electrophoresis Cell Line Amino Acid Sequence on Thu Jul 03 2008 at 01:10 UTC | info | related
 
Biosynthetic thiolase from Zoogloea ramigera. Mutagenesis of the putative active-site base Cys-378 to Ser-378 changes the partitioning of the acetyl S-enzyme intermediate
S F Williams et al.
The Journal of biological chemistry 267 (23), 16041-3 (15 Aug 1992)
info:pmid/1353760
Posted by gjwilliams2 to Serine Non-P.H.S. U.S. Gov't Non-U.S. Gov't Research Support Enzymology Pseudomonadaceae Protein Conformation Site-Directed mutagenesis Molecular Sequence Data kinetics cysteine circular dichroism binding sites Amino Acid Sequence acetylation metabolism genetics BIOSYNTHESIS Acetyl-CoA C-Acetyltransferase on Thu Jul 03 2008 at 01:10 UTC | info | related
 
Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton
C T Walsh, A Schonbrunn, and R H Abeles
The Journal of biological chemistry 246 (22), 6855-66 (25 Nov 1971)
info:pmid/4399475
Posted by gjwilliams2 to Ultraviolet Rays Tritium Thiosemicarbazones Stereoisomerism Spectrophotometry Serine Quaternary Ammonium Compounds Pyruvates Protons proline Phenylhydrazines oxygen nitrogen Models, Chemical kinetics keto acids Hydrogen-Ion Concentration hydrogen Flavin-Adenine Dinucleotide Deuterium D-Amino-Acid Oxidase CHLORINE chemistry Alanine on Thu Jul 03 2008 at 01:10 UTC | info | related
 
Studies on the elimination reaction of D-amino acid oxidase with -amino- -chlorobutyrate. Further evidence for abstraction of substrate -hydrogen as a proton
C T Walsh et al.
The Journal of biological chemistry 248 (6), 1946-55 (25 Mar 1973)
info:pmid/4144104
Posted by gjwilliams2 to Tritium Threonine temperature Swine Spectrophotometry Serine Protons Oxygen Consumption Oxidation-Reduction Osmolar Concentration kinetics Enzymology kidney keto acids Isomerism hydrogen Deuterium D-Amino-Acid Oxidase CHLORINE Catalysis Apoproteins animals Aminobutyric Acids amino acids Alanine on Thu Jul 03 2008 at 01:10 UTC | info | related
 
Mechanistic studies on trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (Ent A) in the biosynthesis of the iron chelator enterobactin
M Sakaitani et al.
Biochemistry 29 (29), 6789-98 (24 Jul 1990)
info:pmid/2144454
Posted by gjwilliams2 to Stereoisomerism analogs & derivatives Serine Research Support, U.S. Gov't, P.H.S. Research Support, Non-U.S. Gov't Oxidoreductases Acting on CH-CH Group Donors Oxidoreductases Oxidation-Reduction Nad molecular structure Models, Chemical kinetics Escherichia coli Proteins enterobactin metabolism Enterobacteriaceae binding sites on Thu Jul 03 2008 at 00:50 UTC | info | related
 
Expressed protein ligation to probe regiospecificity of heterocyclization in the peptide antibiotic microcin B17
R S Roy, O Allen, and C T Walsh
Chemistry & biology 6 (11), 789-99 (Nov 1999)
info:pmid/10574779
Posted by gjwilliams2 to Serine Research Support, U.S. Gov't, P.H.S. Research Support, Non-U.S. Gov't Protein Conformation chemical synthesis Peptides mutagenesis Multienzyme Complexes Molecular Sequence Data Models, Molecular Isomerism genetics Escherichia coli cysteine metabolism Bacteriocins Bacterial Proteins chemistry Anti-Bacterial Agents Amino Acid Sequence on Thu Jul 03 2008 at 00:50 UTC | info | related
 
Inactivation of the Pseudomonas striata broad specificity amino acid racemase by D and L isomers of beta-substituted alanines: kinetics, stoichiometry, active site peptide, and mechanistic studies
D Roise et al.
Biochemistry 23 (22), 5195-5201 (23 Oct 1984)
info:pmid/6439237
Posted by gjwilliams2 to beta-Alanine Trypsin Serine Research Support, U.S. Gov't, P.H.S. Pyridoxal Phosphate Enzymology Pseudomonas Nad Molecular Weight kinetics Isomerism Pharmacology Borates binding sites analysis amino acids Amino Acid Isomerases metabolism analogs & derivatives Alanine on Thu Jul 03 2008 at 00:50 UTC | info | related
 
Dissection of the EntF condensation domain boundary and active site residues in nonribosomal peptide synthesis
Eric D Roche and Christopher T Walsh
Biochemistry 42 (5), 1334-44 (11 Feb 2003)
info:pmid/12564937 | info:doi/10.1021/bi026867m
Posted by gjwilliams2 to Serine Research Support, U.S. Gov't, P.H.S. Research Support, Non-U.S. Gov't Protein Structure, Tertiary Peptide Synthases Peptide Fragments Peptide Biosynthesis Mutagenesis, Site-Directed Multienzyme Complexes Molecular Sequence Data Ligases Hydroxybenzoic Acids Histidine Genetic Complementation Test Escherichia coli Proteins metabolism enterobactin analogs & derivatives cysteamine Catalysis binding sites chemistry amino acids Amino Acid Sequence genetics Alanine on Thu Jul 03 2008 at 00:50 UTC | info | related
 
Characterization of EntF as a serine-activating enzyme
J Reichert, M Sakaitani, and C T Walsh
Protein science : a publication of the Protein Society 1 (4), 549-56 (Apr 1992)
info:pmid/1338974
Posted by gjwilliams2 to analogs & derivatives Serine P.H.S. U.S. Gov't Research Support Recombinant Proteins isolation & purification Peptide Synthases Molecular Sequence Data genetics Enzymology Escherichia coli enterobactin Diphosphates Molecular cloning Base Sequence metabolism Adenosine Triphosphate on Thu Jul 03 2008 at 00:50 UTC | info | related

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