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www.increasesperm.org
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Theriogenology 68 (6), 848-52 (01 Oct 2007)
Theriogenology 69 (2), 252-61 (15 Jan 2008)
www.eurekalert.org
A plentiful ingredient found in human semen drastically enhances the ability of the human immunodeficiency virus (HIV) to cause infection, according to a report in the December 14, 2007, issue of the journal Cell, a publication of Cell Press. The findings help to understand the sexual transmission of HIV and suggest a potential new target for preventing the spread of AIDS, the researchers said. Collaborating research groups in Hannover and Ulm, Germany, show that naturally occurring fragments of so-called prostatic acidic phosphatase (PAP) isolated from human semen form tiny fibers known as amyloid fibrils. Those fibrils capture HIV particles and help them to penetrate target cells, thereby enhancing the infection rate by up to several orders of magnitude.
www.nature.com
Fibres may be more important than viral load in determining transmission rates. A component found in semen can enhance HIV transmission by as much as 100,000-fold, researchers have found. The results, if verified in a clinical setting, could identify a new way to help prevent the spread of the disease.
www.alertnet.org
An ingredient in human semen may actually help the HIV virus infect cells, German researchers said on Thursday. They said naturally occurring prostatic acidic phosphatase or PAP, an enzyme produced by the prostate, can form tiny fibers called amyloid fibrils that can capture bits of the human immunodeficiency virus and usher it into cells.
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