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Ureterosigmoidostomy: long-term results, risk of carcinoma and etiological factors for carcinogenesis.
T Kälble et al.
The Journal of urology 144 (5), 1110-4 (Nov 1990)
info:pmid/2231881
We followed postoperatively 75 patients who underwent ureterosigmoidostomy between 1942 and 1987. Of the patients 30 were asked to undergo routine examination, including fiberoptic sigmoidoscopy with biopsy and analysis of a urine-feces slurry for nitrate, nitrite and nitrosamines in comparison to 20 control volunteers. After a mean observation of 14 years 7 months (1 to 46 years) 64.5% of the patients had bilaterally normal kidneys without any previous complications, 77.5% of the renal units being normal. Sigmoidoscopic biopsy revealed 3 carcinomas at the ureterocolonic junction resulting in an 8.5 to 10.5-fold increased risk of colon carcinoma compared to the general population. The excretion of nitrite and N-nitrosamines was increased, and nitrate excretion was decreased compared to healthy control volunteers, suggesting endogenous formation of nitrosamines by bacterially reduced nitrate and endogenous amines. The urological long-term results of ureterosigmoidostomy are similar to those of conduits. However, the increased incidence of colon carcinoma is not yet proved to be higher than in conduits.
Posted by wolfgangmarkull to Urinary Diversion ureteral obstruction Time Factors risk factors Postoperative Period Nitrosamines Nitrites Nitrates humans Follow-Up Studies Colonic Neoplasms Sigmoid colon adult on Sun May 25 2008 at 09:35 UTC | info | related
 
Physiology and interaction of nitrate and nitrite reduction in Staphylococcus carnosus
H Neubauer and F Götz
Journal of bacteriology 178 (7), 2005-9 (Apr 1996)
info:pmid/8606176
DA - 19960517 IS - 0021-9193 (Print) LA - eng PT - Journal Article RN - 0 (Nitrates) RN - 0 (Nitrites) RN - 9002-93-1 (Octoxynol) RN - EC 1.7.- (Nitrate Reductases) RN - EC 1.7.99.4 (Nitrate Reductase) SB - IM
Posted by ndhoang to Staphylococcus physiology Pharmacology oxygen Oxidation-Reduction Octoxynol Nitrites Nitrite Reductases Nitrates Nitrate Reductases nitrate reductase metabolism growth & development Enzymology enzymes drug effects cytosol on Tue Jan 09 2007 at 17:56 UTC | info | related
 
Cloning, sequencing, and characterization of a gene (narT) encoding a transport protein involved in dissimilatory nitrate reduction in Staphylococcus carnosus
B Fast, P Lindgren, and F Götz
Archives of microbiology 166 (6), 361-7 (Dec 1996)
info:pmid/9082911
DA - 19970328 IS - 0302-8933 (Print) LA - eng PT - Journal Article RN - 0 (Bacterial Proteins) RN - 0 (Carrier Proteins) RN - 0 (DNA Transposable Elements) RN - 0 (Membrane Proteins) RN - 0 (Membrane Transport Proteins) RN - 0 (NarT protein, Staphylococcus carnosus) RN - 0 (Nitrates) RN - 0 (Nitrites) RN - 0 (Plasmids) RN - EC 1.7.- (Nitrate Reductases) RN - EC 1.7.99.4 (Nitrate Reductase) SB - IM
Posted by ndhoang to transformation Staphylococcus Amino Acid Sequence Homology Sequence analysis Sequence Alignment Restriction Mapping Non-U.S.Gov't Research Support genetic Recombination proteins Protein Plasmids plasmid Nitrites Nitrates Nitrate Reductases nitrate reductase mutation Insertional mutagenesis Molecular Sequence Data metabolism Membrane Transport Proteins membrane proteins genetics bacterial Gene Expression Regulation Escherichia coli DNA Transposable Elements DNA Molecular cloning Carrier Proteins Bacterial Proteins analysis amino acids Amino Acid Sequence on Tue Jan 09 2007 at 17:56 UTC | info | related
 
Molecular characterization of the nitrite-reducing system of Staphylococcus carnosus
H Neubauer, I Pantel, and F Götz
Journal of bacteriology 181 (5), 1481-8 (Mar 1999)
info:pmid/10049379
DA - 19990407 IS - 0021-9193 (Print) LA - eng PT - Journal Article RN - 0 (Bacterial Proteins) RN - 0 (DNA Transposable Elements) RN - 0 (Nitrates) RN - 0 (Nitrites) RN - 0 (SirA protein, Salmonella) RN - 0 (Trans-Activators) RN - EC 1.7.- (Nitrite Reductases) RN - EC 2.1.1. (Methyltransferases) RN - EC 2.1.1.107 (uroporphyrin-III C-methyltransferase) SB - IM
Posted by ndhoang to Trans-Activators Staphylococcus Restriction Mapping Non-U.S.Gov't Research Support Nucleic Acid Repetitive Sequences proteins Protein Promoter Regions (Genetics) phenotype oxygen Oxidation-Reduction operon Nitrites Nitrite Reductases Nitrates Insertional mutagenesis Methyltransferases metabolism kinetics genetics Genetic Complementation Test Enzymology DNA Transposable Elements DNA BIOSYNTHESIS Base Sequence Bacterial Proteins Anaerobiosis Aerobiosis on Tue Jan 09 2007 at 17:56 UTC | info | related

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