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Recent "Antineoplastic" articles

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Understanding and exploiting nature's chemical arsenal: the past, present and future of calicheamicin research
J S Thorson et al.
Current pharmaceutical design 6 (18), 1841-79 (Dec 2000)
info:pmid/11102565
Posted by gjwilliams2 to P.H.S. U.S. Gov't Non-U.S. Gov't Research Support Micromonospora DNA damage Molecular cloning Antineoplastic antibiotics BIOSYNTHESIS Anti-Bacterial Agents Aminoglycosides alkynes Pharmacology metabolism chemical synthesis ALKENES on Thu Jul 03 2008 at 00:50 UTC | info | related
 
Vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic
K Shindo et al.
The Journal of antibiotics 46 (7), 1076-81 (Jul 1993)
info:pmid/8360102
Posted by gjwilliams2 to Cultured Tumor Cells metabolism classification Streptomyces molecular structure Nude mice Magnetic Resonance Spectroscopy macrolides Lactams humans Fermentation antitumor Drug Screening Assays Antineoplastic antibiotics Pharmacology purification isolation & chemistry BIOSYNTHESIS Anti-Bacterial Agents animals Aminoglycosides on Thu Jul 03 2008 at 00:50 UTC | info | related
 
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii
Yasushi Ogasawara et al.
Chemistry & biology 11 (1), 79-86 (Jan 2004)
info:pmid/15112997 | info:doi/10.1016/j.chembiol.2003.12.010
Posted by gjwilliams2 to genetics Enzymology Streptomyces DNA Sequence analysis Multigene Family Multienzyme Complexes molecular structure Molecular Sequence Data macrolides Ligases Lactams Intramolecular Transferases Regulator bacterial Genes Molecular cloning Antineoplastic antibiotics metabolism chemistry BIOSYNTHESIS Aminoglycosides on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Isolation and structure elucidation of vicenistatin M, and importance of the vicenisamine aminosugar for exerting cytotoxicity of vicenistatin
Y Matsushima et al.
The Journal of antibiotics 54 (3), 211-9 (Mar 2001)
info:pmid/11372778
Posted by gjwilliams2 to Cultured Tumor Cells structure-activity relationship Streptomyces molecular structure Magnetic Resonance Spectroscopy macrolides Lactams humans Hexoses Glycosides antitumor Drug Screening Assays Physical purification isolation & Antineoplastic antibiotics isolation & purification Anti-Bacterial Agents animals Aminoglycosides Pharmacology chemistry Amino Sugars on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins
M G Marcu, T W Schulte, and L Neckers
Journal of the National Cancer Institute 92 (3), 242-8 (02 Feb 2000)
info:pmid/10655441
Posted by gjwilliams2 to Tumor Suppressor Proteins Tumor Suppressor Protein p53 Cultured Tumor Cells cytology Spleen signal transduction Proto-Oncogene Proteins c-raf Protein Binding Oncogene Protein pp60(v-src) analogs & derivatives Novobiocin mice Intracellular Signaling Peptides and Proteins humans HSP90 Heat-Shock Proteins fibroblasts female Enzyme Inhibitors antagonists & inhibitors Type II DNA Topoisomerases Coumarins metabolism drug effects Carrier Proteins carcinoma drug therapy Breast Neoplasms Western blotting Pharmacology chemistry Antineoplastic antibiotics animals Aminocoumarins on Thu Jul 03 2008 at 00:15 UTC | info | related
 
Antitumor antibiotics: bleomycin, enediynes, and mitomycin
Ute Galm et al.
Chemical reviews 105 (2), 739-58 (Feb 2005)
info:pmid/15700963 | info:doi/10.1021/cr030117g
Posted by gjwilliams2 to P.H.S. Non-P.H.S. U.S. Gov't Non-U.S. Gov't Research Support Cyclic Peptides molecular structure mitomycin Neoplasm Drug resistance Bleomycin Pharmacology chemistry BIOSYNTHESIS Antineoplastic antibiotics animals on Wed Jul 02 2008 at 23:28 UTC | info | related
 
Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: influence of stereochemistry and conformation
F Animati et al.
Molecular pharmacology 50 (3), 603-9 (Sep 1996)
info:pmid/8794900
Posted by gjwilliams2 to Cultured Tumor Cells Heterologous transplantation structure-activity relationship Stereoisomerism drug therapy Ovarian Neoplasms molecular structure Molecular Conformation Molecular Models Nude mice Magnetic Resonance Spectroscopy humans fluorine female Doxorubicin analogs & derivatives Daunorubicin metabolism Type II DNA Topoisomerases drug effects Cell Survival Cell Line Antineoplastic antibiotics toxicity therapeutic use chemistry anthracyclines animals on Wed Jul 02 2008 at 23:28 UTC | info | related
 
Sperm motion analysis in rats treated with adriamycin and its applicability to male reproductive toxicity studies
M Kato et al.
The Journal of toxicological sciences 26 (1), 51-9 (Feb 2001)
info:pmid/11255793
DA - 20010320 IS - 0388-1350 (Print) LA - eng PT - Journal Article RN - 0 (Antibiotics, Antineoplastic) RN - 0 (Antineoplastic Agents) RN - 23214-92-8 (Doxorubicin) SB - IM
Posted by hamiltonthorne to toxicity testis sperm motility Sprague-Dawley rats Organ Size Male IVOS fertility female epididymis drug effects Doxorubicin Drug Dose-Response Relationship body weight Antineoplastic Agents Antineoplastic antibiotics animals on Wed May 23 2007 at 16:28 UTC | info | related
 
Inhibitor of apoptosis-1 (IAP-1) expression and apoptosis in non-small-cell lung cancer cells exposed to gemcitabine
E. Bandala et al.
Biochem Pharmacol 62 (1), 13-9 (2001)
TY - JOUR
Posted by hlhernandez to Antineoplastic Apoptosis gemcitabine IAP-1 A549 cells NF-[kappa]B on Wed Feb 07 2007 at 16:08 UTC | info | related
 
Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial
Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma A randomized controlled trial
S Kawata et al.
British journal of cancer. 84 (7), 886-91 (06 Apr 2001)
info:pmid/11286466 | info:doi/10.1054/bjoc.2000.1716
DA - 20010405 IS - 0007-0920 (Print) LA - eng PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial RN - 0 (Antimetabolites, Antineoplastic) RN - 0 (Antineoplastic Combined Chemotherapy Protocols) RN - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) RN - 0 (alpha-Fetoproteins) RN - 51-21-8 (Fluorouracil) RN - 635-65-4 (Bilirubin) RN - 81093-37-0 (Pravastatin) RN - EC 2.6.1.2 (Alanine Transaminase) SB - IM
Posted by jchardwick to therapy therapeutic use Non-U.S.Gov't Research Support pravastatin Middle Aged methods metabolism Male Liver Neoplasms Hydroxymethylglutaryl-CoA Reductase Inhibitors humans Fluorouracil female therapeutic Embolization drug therapy Drug Administration Schedule cells Hepatocellular carcinoma blood bilirubin Antineoplastic Combined Chemotherapy Protocols Antineoplastic Antimetabolites alpha-Fetoproteins Alanine Transaminase Aged adult administration & dosage 9 on Mon Nov 06 2006 at 15:38 UTC | info | related

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