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Expression of IL-10 in Th memory lymphocytes is conditional on IL-12 or IL-4, unless the IL-10 gene is imprinted by GATA-3.
Hyun-Dong Chang et al.
European journal of immunology 37 (3), 807-17 (Mar 2007)
info:pmid/17304625 | info:doi/10.1002/eji.200636385
Posted by stephr to IL-10 cytokines Tmem on Thu Aug 28 2008 at 18:05 UTC | info | related
 
T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3.
Habiba Chakir et al.
Journal of immunological methods 278 (1-2), 157-69 (Jul 2003)
info:pmid/12957404
GATA3 level used to describe balance...
Posted by stephr to cytokines Tmem on Thu Aug 28 2008 at 17:34 UTC | info | related
 
CD8 T cell dysfunction during chronic viral infection.
Haina Shin and E John Wherry
Current opinion in immunology 19 (4), 408-15 (Aug 2007)
info:pmid/17656078 | info:doi/10.1016/j.coi.2007.06.004
Posted by stephr to exhasution Wherry LCMV review on Tue Aug 19 2008 at 18:02 UTC | info | related
 
Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus.
D Binder et al.
The Journal of experimental medicine 187 (11), 1903-20 (01 Jun 1998)
info:pmid/9607930
depleting CD8s cures anemia, so "exhaustion saves mouse from anemia!"
Posted by stephr to exhaustion anemia LCMV CD8 pathology on Tue Aug 19 2008 at 17:57 UTC | info | related
 
Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus.
D Moskophidis et al.
The Journal of general virology 76 ( Pt 2), 381-91 (Feb 1995)
info:pmid/7531218
first LCMV exhaustion=chronic for high dose-Zinkernagel
Posted by stephr to exhaustion LCMV CD8 on Tue Aug 19 2008 at 17:52 UTC | info | related
 
Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation
Didrik Paus et al.
The Journal of Experimental Medicine 203 (4), 1081-91 (17 Apr 2006)
info:doi/10.1084/jem.20060087
beautiful FACS for Plasma Cells-intracellular HEL, HEL-Alexa conjugation
Posted by stephr to Bcell FACS extrafollicular mz on Mon Aug 11 2008 at 15:22 UTC | info | related
 
SIGN-R1 contributes to protection against lethal pneumococcal infection in mice.
Astrid Lanoue et al.
The Journal of experimental medicine 200 (11), 1383-93 (06 Dec 2004)
info:pmid/15583012 | info:doi/10.1084/jem.20040795
Posted by stephr to notTLR mz on Mon Aug 11 2008 at 13:35 UTC | info | related
 
In Vitro and In Vivo Activation Induces BAFF and APRIL Expression in B Cells
Van Chu et al.
The Journal of Immunology 179 (9), 5947-57 (01 Nov 2007)
how to: intracellular BAFF and APRIL cytospin, FACS
Posted by stephr to Bcell help Bcell on Mon Aug 11 2008 at 13:28 UTC | info | related
 
Short-circuiting long-lived humoral immunity by the heightened engagement of CD40.
Loren D Erickson et al.
The Journal of clinical investigation 109 (5), 613-20 (Mar 2002)
info:pmid/11877469 | info:doi/10.1172/JCI14110
anti-CD40 makes cells go more for extra-follicular vs. GC
Posted by stephr to extrafollicular mz Bcell on Mon Aug 11 2008 at 13:07 UTC | info | related
 
Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response
Blood 105 (4), 1614 (2005)
info:doi/10.1182/blood-2004-07-2507
nice, shows mobilization of plasma cells from BM
Posted by stephr to Bcell on Mon Aug 11 2008 at 12:29 UTC | info | related

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